Results 91 to 100 of about 4,501,989 (341)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Five minutes with Bora Zivkovic: “The blog is a way for me to promote young and new voices, that’s why they call me The Blogfather!” [PDF]
, 2012 One of the best known science writers and bloggers in the online world, Bora Zivkovic is the chief editor and community manager of the Scientific American blogs network.
Blog Admin, Impact of Social Sciences, +1 more
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Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Science In The Media; Reconstruction Of Science In Media Frames
Iranian Journal of Information Processing & Management, 2014 Medialization of science could be defined as “an increasing media attention for scientific issues and an increasing orientation of science towards the media.” There are three key actor include scientists, journalists and public which their interactions ...
Hadi Khaniki, Zarrin Zardar
doaj
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Total SciComm — All out science communication [PDF]
This essay seeks to introduce a philosophy of science communication: Total SciComm or all out science communication. The concept is inspired by the Dutch total football, in which, every player can play at any role.
Ho, Manh-Toan, Ho, Manh-Tung
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Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Optical communication on CubeSats - Enabling the next era in space science
, 2018 CubeSats are excellent platforms to rapidly perform simple space experiments. Several hundreds of CubeSats have already been successfully launched in the past few years and the number of announced launches grows every year.
Biswas, Abhijit +6 more
core +1 more source