Results 111 to 120 of about 14,654,546 (350)
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
Teacher Education: Science or Art? [PDF]
İnönü Üniversitesi Eğitim Fakültesi Dergisi, 2009 While being a teacher-educator is a complex task, the mode to train teacher-educators is yet unclear. This question is even more relevant because education colleges thriving for academic accreditation recruit PhDs with no field experience.
Mira KARNIELI
doaj
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Research Into STS Science Education
Educación Química, 2018 STS science curriculum content includes both the internal workings of the scientific enterprise and the scientific enterprises external interaction with technology and society.
Glen Aikenhead
doaj +1 more source
Math and Science Education Focus Groups: Summary [PDF]
, 2005 Summarizes the causes of low achievement in math and science and strategies for raising student interest, enhancing teacher quality and professional development, and improving curricula and teaching strategies, as discussed at a November 2004 ...
core
Using Cooperative Learning Model to Enhance Academic Performance of Teacher Trainees in Some Selected Topics in Integrated Science at Saint Monica’s College Of Education [PDF]
, 2020 The study sought to investigate the effects of using cooperative learning on female teacher trainees of the Colleges of Education in learning some selected topics in Integrated Science.
Agyei, Amoah
core
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Constructivism, Education, Science, and Technology
Canadian Journal of Learning and Technology, 2003 : The purpose of this paper is to present a brief review of the various streams of constructivism in studies of education, society, science and technology.
Moses A. Boudourides
doaj +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Education SciencesQuantum science and computing represent a vital intersection between science and technology, gaining increasing importance in modern society. There is a pressing need to incorporate these concepts into the K-12 curriculum, equipping new generations with ...
Nancy Holincheck +5 more
doaj +1 more source