Results 151 to 160 of about 2,279,526 (315)

Learning perspectives: Implications for pedagogy in science education.

, 2003
How we understand learning has implications for the learning outcomes we value and how we seek to achieve them particularly when we want to do something about learning.
Cowie, Bronwen
core  

Ethnographies of social science education

Journal of Social Science Education, 2022
Katarina Blennow, Tilman Grammes
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

The influence of context on science curricula: Observations, conclusions and some recommendations for curriculum development and implementation

, 2008
The genesis of this project and book was our experiences of teaching science and science education at various levels in developing countries; in the Pacific and the Caribbean.
Coll, Richard K., Taylor, Neil
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Topics and trends in current science education : 9th ESERA Conference Selected Contributions /

, 2014
Index.Part 1: Overview of the book -- Overview of the book, Catherine Bruguière, Andrée Tiberghien, Pierre Clément -- Part 2: Socio-Scientific Issues -- The Need for a Public Understanding of Sciences, Isabelle Stengers -- Questions Socialement Vives and
Clément, Pierre., Tiberghien, Andrée., Bruguière, Catherine., European Science Education Research Association. International Conference   +3 more
core  

Normativity in Social Science Education and History Education

Journal of Social Science Education, 2015
Maria Olson, Tatjana Zimenkova
doaj   +3 more sources

Research into STS science education

Revista Brasileira de Pesquisa em Educação em Ciências, 2011
STS science curriculum content includes both the internal workings of the scientific enterprise and the scientific enterprise’s external interaction with technology and society.
Glen S. Aikenhead
doaj  

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source