Results 101 to 110 of about 20,984,995 (345)

Mapping Twenty-First-Century General Education Based upon A Convergence Science －Humanistic Conversion of Big History [PDF]

, 2020
Hye Jeong Park
openalex   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, Volume 19, Issue 12, Page 3769-3783, December 2025.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Biophotonics: a marriage of sciences [PDF]

, 2002
Biophotonics denotes a combination of biology and photonics, with photonics being the science and technology of generation, manipulation, and detection of photons, quantum units of light.
Girkin, J.M.
core  

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, Volume 19, Issue 12, Page 3750-3768, December 2025.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

Martini 3: a general purpose force field for coarse-grained molecular dynamics

Nature Methods, 2021
Paulo C. T. Souza, Riccardo Alessandri, J. Barnoud, S. Thallmair, Ignacio Faustino, F. Grünewald, Ilias Patmanidis, H. Abdizadeh, Bart M. H. Bruininks, T. Wassenaar, Peter C. Kroon, Josef Melcr, Vincent Nieto, V. Corradi, H. Khan, J. Domanski, M. Javanainen, H. Martinez-Seara, N. Reuter, R. Best, I. Vattulainen, L. Monticelli, X. Periole, D. Tieleman, A. H. de Vries, S. Marrink   +25 more
semanticscholar   +1 more source

Science, Politics, and Values: The Politicization of Professional Practice Guidelines [PDF]

, 2009
The Connecticut Attorney General’s recent allegations that the Infectious Disease Society of America violated antitrust law through its treatment guidelines for Lyme disease were neither based in sound science or appropriate legal judgment.
Gostin, Lawrence O., Kraemer, John D.
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Teaching trust in science: a critical new focus for science education

Frontiers in Communication
The recent pandemic has revealed the importance of understanding how scientific knowledge is produced, if citizens are to make decisions that protect themselves, their communities, and their nations. Creating such an understanding presents a critical and
Karen Hopkin, Keith Roberts, Bruce Alberts   +2 more
doaj   +1 more source

Hands-on Physical Science Course at Radford University [PDF]

, 1999
Most students in our introductory physical science course are elementary education majors. We are faced with several obstacles in teaching basic science to these students.
Tanaka, T.
core   +1 more source