Results 111 to 120 of about 21,296,625 (392)
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Discover EducationEffective science instruction and associated student learning is reliant upon a strong foundation of teacher content knowledge. This study of the Praxis Ⓡ General Science Content Knowledge Test from May 2006 to June 2016 investigates content knowledge of
Rachel Ndembera +3 more
doaj +1 more source
Manifesto for transparent mathematical modeling: from ecology to general science
Academia BiologyMathematical black-box models, which hide the structure and behavior of the subsystems, currently dominate science. Mechanisms under study remain hidden.
Vyacheslav L. Kalmykov, Lev V. Kalmykov
doaj +1 more source
Science and Technology Section's General Discussion Group: Highlights from Midwinter 2000
Issues in Science and Technology Librarianship, 2000 The article summarizes the Science and Technology Section's General Discussion Group from ALA Midwinter 2000.
Kimberly A. Lyons-Mitchell +1 more
doaj +1 more source
A personalist-phenomenological model of general resurrection in light of current science and medicine [PDF]
, 2018 I have argued that the central Christian doctrine of general resurrection (with particular reference to the Pauline corpus) can and should be understood in a scientifically and philosophically informed context, and have proposed a personalist ...
Danielyan, Edgar
core
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
The State of Science-and-Religion Scholarship At The Turn of the Century [PDF]
, 2012 In this keynote address to the 2000 Science and Religion Colloquium, the author not only describes and assesses the state of religion-and-science scholarship at the turn of the century hut also proposes a new approach for guiding it into the new century.
Wildman, Wesley J.
core +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source