Results 171 to 180 of about 10,899,612 (352)
Molecular Oncology, EarlyView.We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin +10 more
wiley +1 more source
Social science literacy among form four students in Malaysian secondary schools
Journal of Research, Policy & Practice of Teachers & Teacher Education, 2014 An exploratory study was conducted to investigate the social science literacy among form four students in Malaysian secondary schools. Theaim of the study was to explore social science literacy in selected social science subjects, namely ...
Chang Lee Hoon +5 more
doaj
Digital Preservation and Astronomy: Lessons for funders and the funded
, 2011 Astronomy looks after its data better than most disciplines, and it is no coincidence that the consensus standard for the archival preservation of all types of digital assets -- the OAIS Reference Model -- emerged originally from the space science ...
Gray, Norman, Woan, Graham
core
Molecular Oncology, EarlyView.Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik +3 more
wiley +1 more source
Identifying prognostic targets in metastatic prostate cancer beyond AR
FEBS Open Bio, EarlyView.Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng +13 more
wiley +1 more source
Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity
FEBS Open Bio, EarlyView.This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Phenotypic plasticity in a newly established set of EGFR inhibitor‐adapted NSCLC cell lines during adaptation and in established cell lines. Here, we introduce novel sublines of the EGFR‐mutant non‐small cell lung cancer (NSCLC) cell lines HCC827 and HCC4006 adapted to the EGFR kinase inhibitors gefitinib (HCC827rGEFI2μm, HCC4006rGEFI1μm), erlotinib ...
Tharsagini V. Nanthaprakash +6 more
wiley +1 more source
Retinal detachment associated with the splice site mutation c.53-1G>A in the <i>RS1</i> gene: A case report and review of the literature. [PDF]
SAGE Open Med Case RepMeng J, Cai S, Su G.
europepmc +1 more source
THE PERIODS REGULATING THE RECURRENCE OF VITAL PHENOMENA; BEING A GENERAL SUMMARY OF PREVIOUS CONTRIBUTIONS TO PROLEPTICAL SCIENCE. [PDF]
Thomas Laycock
openalex +1 more source