Results 51 to 60 of about 20,984,995 (345)

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source

Cultural Adaptation and Validation of the Turkish Version of the Expanded Prostate Cancer Index Composite

Journal of Urological Surgery
Objective: This study aimed to culturally adapt the Turkish version of the expanded prostate cancer index composite (EPIC) questionnaire form, which evaluates post-treatment functions in prostate cancer (PCa) patients, to investigate whether it is ...
Sahin Kabay
doaj   +1 more source

Citizen Science in Biomedicine: Attitudes, Motivation, and Concerns of the General Public and Scientists in Latvia

Social Sciences, 2023
Citizen science is research carried out by citizens in cooperation with scientists based on scientifically developed methods. Citizen science makes science accessible to the public and promotes public trust. Since there is scarce evidence about attitudes
Alise Svandere, Signe Mežinska, Jekaterina Kaleja, Normunds Kante, Raitis Peculis, Olesja Rogoza, Vita Rovite   +6 more
doaj   +1 more source

The Art, Science, and Engineering of Fuzzing: A Survey [PDF]

IEEE Transactions on Software Engineering, 2018
Among the many software testing techniques available today, fuzzing has remained highly popular due to its conceptual simplicity, its low barrier to deployment, and its vast amount of empirical evidence in discovering real-world software vulnerabilities.
Valentin J. M. Manès, HyungSeok Han, Choongwoo Han, S. Cha, Manuel Egele, Edward J. Schwartz, Maverick Woo   +6 more
semanticscholar   +1 more source

Mitochondrial fatty acid oxidation is stimulated by red light irradiation

FEBS Letters, EarlyView.
Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera, Camille C. Caldeira da Silva, Maiza Von Dentz, Mauricio S. Baptista, Alicia J. Kowaltowski   +4 more
wiley   +1 more source

Injury Risk Estimation Expertise Assessing the ACL Injury Risk Estimation Quiz [PDF]

, 2015
Background: Available methods for screening anterior cruciate ligament (ACL) injury risk are effective but limited in application as they generally rely on expensive and time-consuming biomechanical movement analysis.
Agel J, Cokely ET, Cokely ET, Ekegren CL, Ericsson KA, Ericsson KA, Ericsson KA, Ericsson KA, Gosling SD, Hewett TE, Hewett TE, Hoffman RR, Hopkins WG, Hopkins WG, Kim S, Mann DTY, Myer GD, Myer GD, Myer GD, Nagda SH, Nilstad A, Paolacci G, Peters M, Petushek EJ, Prodromos CC, Stensrud S, Sugimoto D, Ward P, Whatman C, Whatman C, Wiggins M   +30 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

General Anthropology: Between Philosophy and Science

RUDN Journal of Philosophy, 2012
The article seeks to define the grounds of general anthropology as a complex human science. The author considers the preconditions for the formation of general anthropology as a scientific discipline.
J M Reznik
doaj  

Is the Course Working? An Account of Our Development of an Instrument to Measure the Science Attitudes and Skills of Undergraduate Students Outside of Science Disciplines

Teaching & Learning Inquiry: The ISSOTL Journal
After a redesign of our school year structure, our science team developed an introduction to science course focused on teaching science to non-science majors early in their post-secondary studies.
Ellen Watson, Sheryl Gares, Brian Rempel
doaj   +1 more source

Emptiness in psychological science and practice

Psychology in Russia: State of Art, 2016
Psychology is now one of the most popular sciences for young students. But whether academic production or professional practice, it is still in crisis. When we look together at two different approaches we realize the enormous amount of syncretism.
Quintino-Aires J.
doaj   +1 more source