Results 191 to 200 of about 2,545,043 (343)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Prospects and Research Trends of Tuberculosis in Iran: A Bibliometric Study With a Science Mapping Approach. [PDF]

Interdiscip Perspect Infect Dis
Azimi S, Bashardoust B, Mohammadi M.
europepmc   +1 more source

Science Mapping Analysis of COVID-19 Articles Published in Dental Journals. [PDF]

Int J Environ Res Public Health, 2021
Soltani P, Baghaei K, Tavakoli Tafti K, Spagnuolo G.   +3 more
europepmc   +1 more source

Information Science Principles of Machine Learning: A Causal Chain Meta-Framework Based on Formalized Information Mapping [PDF]

Jianfeng Xu
openalex   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

From Stories to Science: Mapping Global Trends in Narrative Medicine Research (2004-2024). [PDF]

Cureus
Chen G, Xu C, Wang K, Wang Z, Xu G, Ji X.   +5 more
europepmc   +1 more source

Knowledge mapping of Computational Thinking and Science, Technology, Engineering, and Mathematics (CT+STEM)

Edi Supriyadi, Joseph G. Taban
openalex   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Towards multiple ontologies in science mapping. A tribute to Loet Leydesdorff. [PDF]

Scientometrics
Rafols I.
europepmc   +1 more source

A Half Century of Research on Childhood and Adolescent Depression: Science Mapping the Literature, 1970 to 2019. [PDF]

Int J Environ Res Public Health, 2021
Zhou M, Bian B, Zhu W, Huang L.
europepmc   +1 more source