Results 111 to 120 of about 20,000,822 (310)

Science policy, science funding, and the science community

open access: yesAcademic Medicine, 1991
The ongoing federal budget crisis has led to extensive debate over how much money the federal government should spend on scientific research. In the struggle for limited funds, many advocacy groups will covet the large sums proposed for science research, and the scientific community may be called upon to justify its large share of the discretionary ...
openaire   +3 more sources

Proceedings of the 57th Annual Meeting of the Arizona-Nevada Academy of Science

open access: yes, 2013
FIFTY SEVENTH ANNUAL MEETING / June 16-19, 2013 / Joint Meeting with the Pacific Division of the American Association for the Advancement of Science / University of Nevada at Las Vegas / Las Vegas, NVAbstracts from the annual meeting of the Arizona ...
Arizona-Nevada Academy of Science
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Proceedings of the 41st Annual Meeting of the Arizona-Nevada Academy of Science

open access: yes, 1997
FORTY FIRST ANNUAL MEETING / April 19, 1997 / The University of Nevada, Las Vegas / Las Vegas, NV / 1996-1997 Annual ReportsAbstracts from the annual meeting of the Arizona-Nevada Academy of Science.1997 Proceedings Supplement / Journal of the Arizona ...
Arizona-Nevada Academy of Science
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Proceedings of the 45th Annual Meeting of the Arizona-Nevada Academy of Science

open access: yes, 2001
FORTY FIFTH ANNUAL MEETING / April 14, 2001 / University of Nevada, Las Vegas / Las Vegas, Nevada / 2000-2001 Annual ReportsAbstracts from the annual meeting of the Arizona-Nevada Academy of Science.This volume is part of the Arizona-Nevada Academy of ...
Arizona-Nevada Academy of Science
core  

Einstein, sacred science, and quantum leaps a comparative analysis of western science, Native science and quantum physics paradigm [PDF]

open access: yes, 2005
ix, 135 leaves ; 29 cm.Science is curiosity about the natural world translated into knowledge; it serves to identify laws and validate hypotheses. The quest for knowledge is influenced by the paradigm of the scientist. The primary object of this study is
University of Lethbridge. Faculty of Arts and Science   +1 more
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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