Results 201 to 210 of about 45,402,882 (239)

Effects of perfusion-guided permissive hypotension and early vasopressin initiation in adults with septic shock: protocol for a multicentre 2×2 factorial randomised controlled trial in Japanese intensive care units. [PDF]

BMJ Open
Endo A, Yamakawa K, Tagami T, Yamamoto R, Umemura Y, Takayama W, Hoshi H, Hayashi Y, Komori A, Yanagisawa T, Hisamune R, Yoshino Y, Murao S, Okubo S, Azumaguchi R, Narita C, Ono T, Masaki T, Shoko T, Yamagiwa T, Takahashi J, Suekane A, Oi Y, Matsuura H, Miura N, Koami H, Kimoto K, Oishi T, Takahashi K, Wada T.   +29 more
europepmc   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

RETRACTED: Yadav et al. A Feature Extraction Using Probabilistic Neural Network and BTFSC-Net Model with Deep Learning for Brain Tumor Classification. <i>J. Imaging</i> 2023, <i>9</i>, 10. [PDF]

J Imaging
Yadav AS, Kumar S, Karetla GR, Cotrina-Aliaga JC, Arias-Gonzáles JL, Kumar V, Srivastava S, Gupta R, Ibrahim S, Paul R, Naik N, Singla B, Tatkar NS.   +12 more
europepmc   +1 more source

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro, Mackenzie Silverman, Maeve C. Lucas, Mariam M. Yousuf, Samuel T. Otey, Stella V. Gray, Brittany Jordan, Madeline D. Kahan, Latanya D. Agurs, Michelle Van Hirtum Das, Deborah Holder, Devin King, Eileen A. Quinn, Ryan Kammeyer, Michael S. Rafii   +14 more
wiley   +1 more source

A Multisource, Multilevel Contextual Database to Support Ending the HIV Epidemic Initiative: Protocol for Design, Construction, Harmonization, and Quality Assurance. [PDF]

JMIR Res Protoc
Rao N, Zheng L, Deihl W, Hernandez-Ramirez RU, Spiegelman D, Davis JL, Humphries D.   +6 more
europepmc   +1 more source

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright, Scotty G. McKay, Jean Ramos Bou, Fen Bao, Vivian B. Truong, Chenyang Li, Li Jiang, Anza B. Memon, E. Mark Haacke, Yulin Ge, Yongsheng Chen   +10 more
wiley   +1 more source

Correction: Feasibility and Preliminary Effects of a Pressure Sensor-Based Exergame on Cognitive and Sensorimotor Frailty in Low-Income Older Adults Receiving Public Community Care Services: Pilot Randomized Controlled Trial. [PDF]

JMIR Aging
Song S, Hahm SC, Chang S, Lee J, Kang H, Lee S, Kim J.   +6 more
europepmc   +1 more source

Correction: Intermediate knowledge enhanced the performance of the amide coupling yield prediction model. [PDF]

Chem Sci
Zhang C, Lin Q, Yang C, Kong Y, Yu Z, Liao K.   +5 more
europepmc   +1 more source