Results 71 to 80 of about 45,402,882 (239)

Science and science education: Ideas and practices of science teachers in high school in Cambina/Angola

open access: yesAmazônia, 2011
In this article, we present an outline of a qualitative research approach in narrative, developed with high school science teachers in the province of Cabinda, Angola.
Juliana Lando Canga   +2 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

South Carolina Governor's School for Science and Mathematics [PDF]

open access: yes
This gives information about the Governor's School for Science and ...
South Carolina Governor's School for Science and Mathematics
core  

The Predictive Effects of School Safety on Southeast Asian Grade 8 Students’ Science Achievement in TIMSS 2015

open access: yesJurnal Pendidikan IPA Indonesia, 2019
This research explored the predictive effects of school safety on science achievement among Southeast Asian eighth graders in TIMSS 2015. In this research, principals’ responses of School Discipline Problems Scale, teachers’ responses of Safe and Orderly
Y. F. Lay, K. T. Ng
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Representations of Nature of Science in School Science Textbooks

open access: yes, 2017
The development of scientific literacy is a major goal of school science education throughout the world (e.g., Next Generation Science Standards [NGSS], Australian Curriculum and Reporting Authority [ACARA], 2015; NGSS Lead States, 2013), and a necessary
McDonald, Christine   +2 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Importance of pre-school science education

open access: yesSHS Web of Conferences, 2017
Considering this aspect of the study, the objective of the study is determining the importance of science education in pre-school period. In this research, two open-ended questions were asked to the prospective teachers. In these questions, the focus was
Kaçan Sibel Demir, Çelikler Dilek
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

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