Results 111 to 120 of about 5,361,695 (314)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Science and the struggle for relevance

open access: yes, 2010
This thesis deals with struggles for relevance of university researchers, their efforts to make their work correspond with ruling standards of relevance and to influence these standards.
Hessels, L.K.   +2 more
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Causal theory error in college students' understanding of science studies. [PDF]

open access: yesCogn Res Princ Implic, 2022
Seifert CM   +3 more
europepmc   +1 more source

European Studies in Philosophy of Science (ESPS) [PDF]

open access: yes
Book Series: European Studies in Philosophy of Science (ESPS) Editors: Dennis Dieks; Maria Carla Galavotti; Wenceslao J. Gonzalez This new series results from the synergy of EPSA - European Philosophy of Science Association - and PSE - Philosophy ...
GALAVOTTI, MARIA CARLA   +2 more
core  

Cover of Alcohol, Science and Society: Twenty-nine Lectures with Discussion as given at the Yale Summer School of Alcohol Studies

open access: yes, 1945
Cover of Alcohol, Science and Society: Twenty-nine Lectures with Discussion as given at the Yale Summer School of Alcohol Studies, After the first session of what would become an annual Summer School of Alcohol Studies in 1943, there was a strong demand ...

core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Using electronic health records to streamline provider recruitment for implementation science studies. [PDF]

open access: yesPLoS One, 2022
Okorie CL   +4 more
europepmc   +1 more source

ADS505 - Local Government / Faculty of Administrative Science & Policy Studies [PDF]

open access: yes, 2018
The local government of today is required to conform to new norms and standards to become more professional, skilled, economical and responsive. This course examines various theories on local government and studies its application in a Malaysian context.
UiTM, Faculty of Administrative Science & Policy Studies
core  

Home - About - Disclaimer - Privacy