Results 191 to 200 of about 5,361,695 (314)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Unveiling Bias: Examining the Influence of Positive Results on Ergogenic Aids in Published Sports Science Studies. [PDF]

Sports Med Int Open
Marocolo M, Mota GR, Rodrigues AB, Leite RCM, Hohl R, Paixão RCD, Souza HLR, Meireles A, Arriel R.   +8 more
europepmc   +1 more source

Computer approaches for the handling of large social science data files

, 1967
Statement of responsibility on cover reads: Ithiel de Sola Pool, James M. Beshers, Stuart McIntosh, and David GriffelCover title"January 1967.""1687"--handwritten on coverA progress report to the National Science Foundation GS ...
McIntosh, Stuart D., Griffel, David M., Pool, Ithiel de Sola, 1917-1984, Beshers, James M.   +3 more
core  

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

What have we learned from basic science studies on idiopathic pulmonary fibrosis? [PDF]

Eur Respir Rev, 2019
Yanagihara T, Sato S, Upagupta C, Kolb M.   +3 more
europepmc   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Reflections on Basic Science Studies Involving Low Doses of Ionizing Radiation. [PDF]

Health Phys, 2018
Paunesku T, Woloschak G.
europepmc   +1 more source

Perspective (Institute for Christian Studies)

, 1999
Two new professors at once [Jonathan Chaplin Senior Member in Political Theory and Adrienne Dengerink Chaplin Senior Member in Aesthetics], From the President: Community service [non-academic activities of ICS faculty], Thanks for Vandervennen for ...
Meiboom, John, Fernhout, Harry, Institute for Christian Studies, Hart, Carroll Guen, Hart, Hendrik, VanderVennen, Robert E., Vandervelde, George   +6 more
core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source