Results 231 to 240 of about 175,781 (305)

Correction: Oregon primary care providers as a frontline defense in the War on Melanoma™: improving access to melanoma education. [PDF]

Front Med (Lausanne)
Becker AL, Nelson JH, Verdieck-Devlaeminck A, Berry EG, Orfaly VE, Stoos ER, Tran J, Latour E, Sahni VN, Xu S, Babcock M, Bar A, Becevic M, Chan C, Chisholm D, Diehl K, Edison K, Ferris LK, Foltz EA, Geller AC, Jacobe H, Johnson MM, Kinghorn P, Leitenberger J, Ludzik J, McClanahan D, Mengden-Koon S, Nelson K, Petering R, Prasad S, Roscher A, Savory S, Smith EH, Swetter SM, Tofte S, Weinstock MA, White K, Wisco O, Witkowski A, Leachman SA.   +39 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

The Impact of Adverse News About the Gaza War on the Health of Iranian Elderly People: A Qualitative Study. [PDF]

Health Sci Rep
Ahmadi Marzaleh M, Jalali K, Peyravi M, Keshavarzi MH, Rezaee R, Moazam Fard M.   +5 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Assessment of agricultural region dynamics using object contour properties from Sentinel-2 images. [PDF]

PLoS One
Nikulin S, Sergieieva K, Kovrov O, Kozhevnykov A, Korobko O.   +4 more
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Distal phalanx of the hand's digit as unusual autologous biological tissue acting as a contaminating foreign body in a combat patient with ballistic pelvic injury: a case report from war in Ukraine. [PDF]

Int J Emerg Med
Lurin I, Khoroshun E, Nehoduiko V, Shypilov S, Gorobeiko M, Dinets A.   +5 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Primary repair for retroperitoneal rectal injuries in modern warfare: selective progress, not dogma. [PDF]

Trauma Surg Acute Care Open
Henry R, Barrett C, Loss L.
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source