Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Enhancing Soldiers for Future Warfare: Good Science; Bad Ethics? [PDF]
Sci Eng EthicsEvans NG, L Gross M, Shandler R.
europepmc +1 more source
Bourdieusian political theory and social science: the field of war correspondence 1990-2003
, 2007 Timothy Markham
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Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Health Care for Military Environmental Exposure Concerns. [PDF]
Med CareMcAndrew LM, Bloeser K.
europepmc +1 more source
American Economy and the Government Activity after the World War II(Social Science) [PDF]
, 1975 安夫 塩谷, Yasuo Shiotani
openalex
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Effects of predicted Khamisiyah exposure on default mode network resting state functional connectivity in Gulf War Veterans. [PDF]
Front ToxicolChao LL, Torrisi S.
europepmc +1 more source
Science for Architecture: Designing Architectural Research in Post-War Sweden
, 2012 Frida Rosenberg
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