Results 51 to 60 of about 1,688,715 (313)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The Aesthetic and Formative values of Mural Painting Scenes in Ancient Egyptian Art As a Suggested Introduction to Appreciating Contemporary Wooden Murals

open access: yesJournal of Architecture, Art & Humanistic Science
The research deals with studying the aesthetic and plastic values of mural scenes in ancient Egyptian art and using them as a suggested entry point for appreciating contemporary wooden murals, by clarifying the importance of wall painting in general and ...
Dr. Dalia Mohamed Mahmoud Sharaf Lecturer of Art History and Appreciation, Department of Art Education, Faculty of Specific Education, Alexandria University   +2 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Baby Basics Project: in-hospital education class for new parents [PDF]

open access: yes, 2021
The Baby Basics Project is an in-hospital education class for new parents. The curriculum was developed to guide and assist health care professionals in educating new parents. This project has been designed with Roy’s Adaptation Model of Nursing to help
University of Lethbridge. Faculty of Health Sciences   +1 more
core  

Epistemological problems of human sciences and education [PDF]

open access: yesAlteridad : Revista de Educación, 2005
El campo de la epistemología es un mundo de conflictos, en ese sentido es mejor plantearse el problema epistemológico desde la visión de un sector de diferencias y luchas constantes, de un mundo de diversidad en el que las posiciones llegan a ser ...
Darwin Reyes Solís
doaj  

Considering Science Education [PDF]

open access: yesScience, 2008
I consider science education to be critically important to both science and the world, and I shall frequently address this topic on this page. Let9s start with a big-picture view. The scientific enterprise has greatly advanced our understanding of the natural world and has thereby enabled the creation of countless medicines and useful devices.
openaire   +2 more sources

Promoting Science Education [PDF]

open access: yesJAMA, 2010
President Obama has called on scientists and health professionals to stand side-by-side with entertainers and athletes to “show young people how cool science can be.”1 As part of his Educate to Innovate campaign,1 the President is promoting science education, with a focus on activities outside of public school classrooms.
Marilyn, Winkleby, Judith, Ned
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

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