Results 101 to 110 of about 9,825,591 (304)
Abu Ali ibn Sino’s scientific heritage related to pedagogy [PDF]
This article discusses the scientific heritage and views of the great scientist Abu Ali ibn Sina, who contributed to world civilization, on the upbringing of the future generation, the science of pedagogy, and his ...
Mubinaxon Xayrullo-qizi Xirmonboyeva +1 more
core
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
From scientific communication to public knowledge : the scientific article web published as a knowledge base [PDF]
, 2005 Linking Electronic published scientific articles to Web ontologies is a cognitive tool of which its impacts and possibilities are far from being evaluated.
Marcondes, Carlos Henrique
core +1 more source
The relation between engineering and science
Revista Facultad de Ingeniería Universidad de Antioquia, 2004 Starting from the definition of science it is shown how it is a central fundament of modern engineering. However, science is only one of its components, because long before science was incorporated to engineering this profession already existed as a ...
Asdrúbal Valencia Giraldo
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Examining the Challenges of Scientific Workflows
, 2007 Workflows have recently emerged as a paradigm for representing and managing complex distributed scientific computations and therefore accelerate the pace of scientific progress.
Gannon, Dennis +9 more
core +2 more sources
Systems Transdisciplinary Approach in the General Classification of Scientific Approaches [PDF]
, 2019 The development of systems thinking and systems worldview needs new types of system approaches. New types of systems approaches should find their place in the appropriate classification of scientific approaches.
Mokiy, Vladimir
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source