Results 31 to 40 of about 30,692 (242)

Situating Expertise: Lessons from the HIV/AIDS Epidemic

Global Challenges, 2018
How do Scientific Advisory Committees (SACs) frame the relationship between political agency and expertise in their work? What are the political implications of the ways in which SACs legitimate or obscure specific forms of political agency?
Lauren Paremoer
doaj   +1 more source

Detection and evaluation of signals associated with exposure to individual and combination of medications in pregnancy: a signal detection study protocol

BMJ Open, 2023
Introduction Considering the high prevalence of polypharmacy in pregnant women and the knowledge gap in the risk–benefit safety profile of their often-complex treatment plan, more research is needed to optimise prescribing.
Christopher Yau, Catherine Nelson-Piercy, Krishnarajah Nirantharakumar, Anuradhaa Subramanian, Peter Brocklehurst, Sinead Brophy, Helen Dolk, Muhammad Usman, Jingya Wang, Colin McCowan, Holly Hope, Jonathan Kennedy, Siang Ing Lee, Amaya Azcoaga-Lorenzo, Gillian Santorelli, Mairead Black, Christine Damase-Michel, Ngawai Moss, Katherine Phillips, Kelly-Ann Eastwood, Kathryn Mary Abel, Lisa Kent, Adeniyi Fagbamigbe, Dermot OReilly, Steven Wambua, Megha Singh, Mohamed Mhereeg, Neil Cockburn, Sudasing Pathirannehelage Buddhika Hemali Sudasinghe   +28 more
doaj   +1 more source

Animal‐Assisted Activities With Therapy Dogs in Pediatric Oncology: A Multicenter Survey of the Current Status, Implementation, and Challenges in Germany, Austria, and Switzerland

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Animal‐assisted activities (AAAs) with therapy dogs have shown positive effects on patient well‐being and quality of life in various areas of medicine, including pediatric oncology. However, research on this topic is limited. The aim of this study is to present the current status of AAA in pediatric oncology in Germany, Austria, and
Jan‐Marius Wedig, Birgit Burkhardt, Christof M. Kramm, Kira Ostermann, Sarah C. Goretzki, Uta Dirksen, Nico Kurpiers, Michael M. Schündeln   +7 more
wiley   +1 more source

Perspective on the use of LNT for Radiation Protection and Risk Assessment by the U.S. Environmental Protection Agency

Dose-Response, 2009
The U.S. Environmental Protection Agency (EPA) bases its risk assessments, regulatory limits, and nonregulatory guidelines for population exposures to low level ionizing radiation on the linear no-threshold (LNT) hypothesis, which assumes that the risk ...
Jerome S. Puskin PhD
doaj   +1 more source

Ethics review of studies during public health emergencies - the experience of the WHO ethics review committee during the Ebola virus disease epidemic

BMC Medical Ethics, 2017
Background Between 2013 and 2016, West Africa experienced the largest ever outbreak of Ebola Virus Disease. In the absence of registered treatments or vaccines to control this lethal disease, the World Health Organization coordinated and supported ...
Emilie Alirol, Annette C. Kuesel, Maria Magdalena Guraiib, Vânia de la Fuente-Núñez, Abha Saxena, Melba F. Gomes   +5 more
doaj   +1 more source

NATIONAL INSTITUTIONS ESTABLISHED IN ACCORDANCE WITH THE PARIS PRINCIPLES, ENGAGED INTO THE PROMOTION AND PROTECTION OF HUMAN RIGHTS IN THE SYSTEM OF INTERNAL MEANS OF SECURITY

Конституційно-правові академічні студії, 2021
The purpose of the article is to clarify the place of national institutions engaged in the promotion and protection of human rights in the system of domestic means created in accordance with the Paris Principles.
Lyudmyla Deshko
doaj   +1 more source

On Hierarchical Composite Endpoints in Pediatric Cancer Supportive Care: Illustrative Examples From Two Multi‐Center Phase‐III Randomized Clinical Trials

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier, Mark Zobeck, Adam J. Esbenshade, Christopher C. Dvorak, Lillian Sung, David Freyer, Sarah Alexander, Etan Orgel, Nicole J. Ullrich, Zach Prudowsky, Brian Fisher, Caitlin W. Elgarten   +11 more
wiley   +1 more source

Silent Spring, the 50^th anniversary of Rachel Carson’s book

BMC Ecology, 2012
Editorial David Pimentel is a professor of ecology and agricultural sciences at Cornell University, Ithaca, NY 14853–0901. His Ph.D. is from Cornell University and had postdoctoral research at the University of Chicago, MIT, and fellowship at Oxford ...
Pimentel David
doaj   +1 more source

Implementation of a new clinical and organisational practice to improve access to primary care services: a protocol for an effectiveness-implementation hybrid study

BMJ Open, 2022
Introduction In Canada, as in most Organisation for Economic Co-operation and Development countries, healthcare systems face significant challenges in ensuring better access to primary care. A regional healthcare organisation in Quebec (Canada) serving a
Arnaud Duhoux, Marie-Pierre Gagnon, Jean-Paul Fortin, Maude Laberge, Andrew Freeman, Mylaine Breton, Nancy Côté, Rébecca Chouinard, El Kebir Ghandour, Elisabeth Martin, Ivy Bourgeault   +10 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source