Results 51 to 60 of about 977,510 (303)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Scientific capacity development for environmental issues: reflections from practice

Frontiers in Sustainability
Scientific capacity development and knowledge exchange are widely acknowledged as central components for addressing global environmental problems. The notions of capacity development or capacity building are used widely with divergent meanings and have ...
Bård Hobæk, Sara Plassnig, Kathinka Fürst, Hans Nicolai Adam, Hans Fredrik Veiteberg Braaten, Kine Bæk, Christoffer Grønstad, Rachel Hurley, Thorjørn Larssen, Yan Lin, Ingrid Nesheim, Luca Nizzetto, Marianne Olsen, Eirik Hovland Steindal   +13 more
doaj   +1 more source

STRENGTHENING STUDENT CAPACITY IN THE PUBLICATION OF SCIENTIFIC PAPERS

EDU-KATA, 2023
The purpose of this study is to determine the strengthening of student capacity in writing scientific papers. The research method used is qualitative descriptive research, as for the power collection techniques used include; observation, interviews and documentation.
Muchamad Suradji, Siti Rahayu Nasichatu Muslimatin   +1 more
openaire   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Politics and the Erosion of Federal Scientific Capacity: Restoring Scientific Integrity to Public Health Science

American Journal of Public Health, 2007
Our nation’s health and prosperity are based on a foundation of independent scientific discovery. Yet in recent years, political interference in federal government science has become widespread, threatening this legacy. We explore the ways science has been misused, the attempts to measure the pervasiveness of this problem, and the effects on our long-
Kathleen M, Rest, Michael H, Halpern
openaire   +3 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Valorisation of Winery By-Products: Revealing the Polyphenolic Profile of Grape Stems and Their Inhibitory Effects on Skin Aging-Enzymes for Cosmetic and Pharmaceutical Applications

Molecules
Grape (Vitis vinifera L.) stems, a by-product of winemaking, possess significant potential value due to their rich polyphenolic composition, which allows their exploitation for cosmetic and pharmaceutical applications.
Rui Dias-Costa, Concepción Medrano-Padial, Raquel Fernandes, Raúl Domínguez-Perles, Irene Gouvinhas, Ana Novo Barros   +5 more
doaj   +1 more source

Exploration and practice of cultivating nursing undergraduates' scientific research and innovation ability [PDF]

Jichu yixue yu linchuang, 2020
To improve nursing students' research capacity, School of Nursing, PUMC explored the mode of scientific research and teaching for nursing undergraduates which meet the needs of healthcare in China and so to develop an integrated and systematic program ...
ZOU Hai-ou, GUO Ai-min, LI Yu-ling
doaj  

The estimated and look-ahead model of scientific and technical capacityof region [PDF]

Экономика региона, 2012
This paper studies the impact of scientific and technical capacity of Russian regions to the possibility of their sustainable development in the modern world.
Anna Vital'evna Zolotukhina , Marina Valer'evna Frants   +1 more
doaj   +1 more source