Results 61 to 70 of about 5,647,510 (295)

Scientific Computing in the Cloud

Computing in Science & Engineering, 2010
We investigate the feasibility of high performance scientific computation using cloud computers as an alternative to traditional computational tools. The availability of these large, virtualized pools of compute resources raises the possibility of a new compute paradigm for scientific research with many advantages.
John J. Rehr, Fernando D. Vila, Jeffrey P. Gardner, Lucas Svec, Micah Prange   +4 more
openaire   +2 more sources

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye, Chimezie Okwuonu, Evelyn Idam, Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Zinnah Aloziem, Blossom Amamchukwu, Patience Elimia, Mkpoikanabasi Obot‐Obot, Henry Mbakwe, Praises Maduagwuna, Olatunji Akinrodoye, Chiamaka Anyanwu, Benjamin Anyanwu, Adedamola Akinsiku, Oluwatoyin A. Akinsiku, Muzamil O. Hassan, Fatiu A. Arogundade, Olalekan E. Ojo, Homayemem Weli, Jesupelumi Adenihun, Aderemi Adelaja, Ebun Bamgboye, Olalekan Olatise, Ade E. Faponle, Ayoola Odeyemi, Michael Muoka, Stephen Asaolu, Qudrat Busari, Blessing Dawudu, Michael Naiyeju, Rasheed A. Balogun   +33 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Accelerating Scientific Computing in the Post-Moore’s Era

ACM Transactions on Parallel Computing, 2020
Novel uses of graphical processing units for accelerated computation revolutionized the field of high-performance scientific computing by providing specialized workflows tailored to algorithmic requirements.
Kathleen E. Hamilton, Catherine D. Schuman, Steven R. Young, R. Bennink, N. Imam, T. Humble   +5 more
semanticscholar   +1 more source

Fuzzy Fractional Differential Equation Involving the Fuzzy Conformable Derivative and the α−Semigroups

The Scientific World Journal
In this work, we discuss solutions to the abstract Cauchy problem of fuzzy conformal fractional. In addition, the method of fuzzy fractional semigroups is used to obtain analytical solutions to the fractional differential equation.
Fouad Ibrahim Abdou Amir, Aziz El Ghazouani, M’hamed El Omari, Said Melliani   +3 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Curvature controlled defect dynamics in topological active nematics

Scientific Reports, 2017
We study the spatiotemporal patterns that emerge when an active nematic film is topologically constraint. These topological constraints allow to control the non-equilibrium dynamics of the active system.
Francesco Alaimo, Christian Köhler, Axel Voigt   +2 more
doaj   +1 more source

Generalization of Convolutional Neural Networks for ECG Classification Using Generative Adversarial Networks

IEEE Access, 2020
Electrocardiograms (ECGs) play a vital role in the clinical diagnosis of heart diseases. An ECG record of the heart signal over time can be used to discover numerous arrhythmias.
Abdelrahman M. Shaker, Manal Tantawi, Howida A. Shedeed, Mohamed F. Tolba   +3 more
doaj   +1 more source

Large-Scale Protein Interactions Prediction by Multiple Evidence Analysis Associated With an In-Silico Curation Strategy

Frontiers in Bioinformatics, 2021
Predicting the physical or functional associations through protein-protein interactions (PPIs) represents an integral approach for inferring novel protein functions and discovering new drug targets during repositioning analysis.
Yasmmin Côrtes Martins, Artur Ziviani, Marisa Fabiana Nicolás, Ana Tereza Ribeiro de Vasconcelos   +3 more
doaj   +1 more source