Results 121 to 130 of about 4,013,520 (312)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Origin and decline of the scientific discipline Descriptive Geometry

Educação Matemática Debate
Descriptive Geometry originated with the creation of the École Centrale des Travaux Publics, later renamed École Polytechnique. Two arts — Architecture and Fortification — were taken as teaching subjects, giving rise to this scientific discipline.
Ana Mary Fonseca Barreto de Almeida, Gert Schubring   +1 more
doaj   +1 more source

Demarcation of Scientific Disciplines

Epistemology & Philosophy of Science
This response article to A.Yu. Antonovsky and T.D. Sokolova’s work, “Types of Nature and Communicative Dimensions of Disciplinary Differentiation”, challenges the foundational assumption of their article that it is possible to analyze science as a “whole” entity, which can then be divided into separate disciplines based on communicative criteria.
openaire   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Scientific discipline

, 2022
Robert West, Susan Michie
openaire   +2 more sources

Retail design: lighting as an atmospheric tool, creating experiences which influence consumers’ mood and behaviour in commercial spaces [PDF]

, 2009
Retail design is no new discipline, but a scientific approach is of rather recent date. Since atmosphere has been proven to have an influence on consumer’s behaviour from a marketing point of view, this Ph.D. focuses on the designers’ perspective.
Christiaans, Henri, Quartier, Katelijn, Van Cleempoel, Koenraad   +2 more
core  

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

CONSIDERATIONS CONCERNING THE ROLE OF ACCOUNTING AS INFORMATIONAL SYSTEM AND ASSISTANCE OF DECISION [PDF]

The accreditation of accounting as scientific discipline is far from being achieved. In our attempt to establish the status of accounting as a science, we have used the current understanding of the term, and the contemporary perspectives on know-ledge in
Cristian Dragan, Valeriu Brabete
core  

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Data analysis and interpretation of UVSP and other experiments on board solar maximum mission [PDF]

During the period of this contract (February 1 1980 to February 1987) there were two separate efforts involved: one was programmetric, i.e., the coordination of scientific working groups and the organization of workshops in the solar physics discipline ...
Wu, S. T.
core   +1 more source