Results 51 to 60 of about 909,869 (300)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Using of world experience of land managers training for sustainable development of agrarian education in Ukraine.

Agricultural and Resource Economics, 2015
Content of the using of world experience of land managers training for sustainable development of agrarian education in Ukraine has been shown. The characteristics of main problems and analysis of conceptual matters of high agrarian education in ...
Іryna Kоshkalda, Aleksandr Knyaz, Volodymyr Тyshkovets   +2 more
doaj  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Is the Search for God Fact(oid) or Fiction? [PDF]

, 2012
This essay opens with an presentation of the postmodern crises of knowledge and method in both the scientific and the theological disciplines. There is potential for science and theology to work through these crises together.
Clingerman, Forrest
core   +1 more source

Ateism kui nõukogude teadus [PDF]

, 2012
Atheism as a Soviet Science Atko Remmel, UT Faculty of Theology The following questions will be addressesd in the talk: To which extent were Soviet anti-religion practices scientifically grounded?
Remmel, Atko
core   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Bridging Physics and Biology Teaching through Modeling [PDF]

, 2013
As the frontiers of biology become increasingly interdisciplinary, the physics education community has engaged in ongoing efforts to make physics classes more relevant to life sciences majors.
Anne-Marie Hoskinson, Benjamin M. Zwickl, Brewer Carol A., Brian A. Couch, Brooker R., Chabay R. W., Cummings K., Etkina E., Giancoli D. C., Halloun I. A., Kathleen A. Hinko, Knight R. D., Levins R., Marcos D. Caballero, National Research Council, National Research Council, National Research Council, National Research Council, National Science Board, Raven P., Reece J. B., Rice J., Serway R. A., Starfield A. M.   +23 more
core   +3 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Recreation as a scientific discipline and its historical aspects [PDF]

Pedagogìka, Psihologìâ ta Mediko-bìologìčnì Problemi Fìzičnogo Vihovannâ ì Sportu, 2012
Purpose of work - to show an importance of recreation measures for forming, renewal, strengthening and saving of students' health. The analysis of recreation measures is resulted in educational space of higher educational establishment.
Zaycev V.P., Iermakov S.S., Manycharyan S.V., Fedyay I.A.   +3 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source