Results 31 to 40 of about 22,383,729 (330)

Nanoparticles‐induced potential toxicity on human health: Applications, toxicity mechanisms, and evaluation models

MedComm, 2023
Nanoparticles (NPs) have become one of the most popular objects of scientific study during the past decades. However, despite wealth of study reports, still there is a gap, particularly in health toxicology studies, underlying mechanisms, and related ...
Lihui Xuan, Zhao Ju, M. Skonieczna, Pingkun Zhou, Ruixue Huang   +4 more
semanticscholar   +1 more source

Nonspecific Impurities in Pharmaceutical Substances: Characteristics of Test Methods

Регуляторные исследования и экспертиза лекарственных средств, 2019
One of the prerequisites of efficacy and safety of finished pharmaceutical products is the quality of pharmaceutical substances used in their production.
Yu. R. Biglova, N. V. Gadasina, T. N. Bokovikova, E. L. Kovaleva, S. A. Nemykina, T. V. Morgunova, T. V. Masterkova, L. A. Stronova, E. P. Gernikova   +8 more
doaj   +1 more source

Pharmacogenetic Approaches to Enhancing Efficacy and Safety of Statins as Illustrated by the Example of Atorvastatin

Безопасность и риск фармакотерапии, 2020
Statins are efficacious lipid-lowering drugs used for prevention of cardiovascular complications in patients with high blood cholesterol. The efficacy and safety of this group of drugs is largely determined by genetic factors. The aim of the study was to
R. Ye. Kazakov, O. A. Checha, I. A. Mazerkina, E. Yu. Demchenkova, T. A. Aleksandrova, V. A. Evteev, S. A. Belkov, A. B. Prokofiev   +7 more
doaj   +1 more source

Experience with the use of pharmacopoeial reference material for the activity of measles vaccine

Вопросы вирусологии, 2023
Introduction. Due to the increased incidence of measles in Russia and in many other regions of the world, vaccines for the measles prevention are especially in demand. Ensuring the quality of the measles vaccine for effective disease prevention is within
Anna S. Binyatova, Tatyana N. Yunasova, Rauza A. Volkova, Alexey Yu. Butirskiy, Tatyana N. Ilyasova, Karine А. Sarkisyan, Artashes A. Movsesyants   +6 more
doaj   +1 more source

International Approaches to Regulation of Medicinal Products Containing Viable Human Cells

Биопрепараты: Профилактика, диагностика, лечение, 2018
The intensive development of cellular technologies stipulates the introduction at the global level of medicinal products based on viable human cells, which in most countries are referred to as biomedical cell products. The authors conducted a comparative
E. V. Melnikova, A. A. Goryaev, M. V. Savkina, O. V. Merkulova, A. A. Chaplenko, O. A. Rachinskaya, I. S. Semenova, G. A. Trusov, V. A. Merkulov   +8 more
doaj   +1 more source

Comparative Dissolution Kinetics of Several Multisource Thioctic Acid Products

Регуляторные исследования и экспертиза лекарственных средств, 2022
The relationship between dissolution and bioavailability is an example of the interdependency between the quality of a medicinal product and its safety and efficacy.
G. F. Vasilenko, L. M. Krasnykh, M. V. Zhuravleva, A. B. Prokofiev, G. I. Gorodetskaya, V. V. Smirnov, N. D. Bunyatyan   +6 more
doaj   +1 more source

Evaluation and Management of the Child and Adult With Fontan Circulation: A Scientific Statement From the American Heart Association.

Circulation, 2019
It has been 50 years since Francis Fontan pioneered the operation that today bears his name. Initially designed for patients with tricuspid atresia, this procedure is now offered for a vast array of congenital cardiac lesions when a circulation with 2 ...
J. Rychik, A. Atz, D. Celermajer, B. Deal, M. Gatzoulis, M. Gewillig, T. Hsia, D. Hsu, A. Kovacs, B. McCrindle, J. Newburger, N. Pike, M. Rodefeld, D. Rosenthal, K. Schumacher, B. Marino, Karen K Stout, G. Veldtman, A. Younoszai, Y. D'udekem   +19 more
semanticscholar   +1 more source

Resistant Hypertension: Detection, Evaluation, and Management: A Scientific Statement From the American Heart Association.

HYPERTENSION, 2018
Resistant hypertension (RH) is defined as above-goal elevated blood pressure (BP) in a patient despite the concurrent use of 3 antihypertensive drug classes, commonly including a long-acting calcium channel blocker, a blocker of the renin-angiotensin ...
R. Carey, D. Calhoun, G. Bakris, R. Brook, S. Daugherty, C. Dennison-Himmelfarb, B. Egan, J. Flack, S. Gidding, E. Judd, D. Lackland, Cheryl L. Laffer, C. Newton‐Cheh, Steven M. Smith, S. Taler, S. Textor, T. Turan, W. White   +17 more
semanticscholar   +1 more source

Analysis of Global Patenting Trends in Radiopharmaceutical Industry: Diagnostics, Therapy, and Theranostics

Регуляторные исследования и экспертиза лекарственных средств
INTRODUCTION. Radiopharmaceuticals play a crucial role in modern nuclear medicine, offering effective methods for cancer diagnostics, treatment, and theranostics.
M. Yu. Anikeeva, Yu. D. Aleksandrov, Yu. A. Gorbunova, N. V. Popov, A. S. Koshevenko, V. V. Ivashchenko, D. S. Ivanova, E. D. Nikolaeva, A. V. Stepanova, D. I. Fedorova   +9 more
doaj   +1 more source

Peer Evaluation of Video Lab Reports in a Blended Introductory Physics Course

, 2014
The Georgia Tech blended introductory calculus-based mechanics course emphasizes scientific communication as one of its learning goals, and to that end, we gave our students a series of four peer-evaluation assignments intended to develop their abilities
Aiken, John M., Caballero, Marcos D., Douglas, Scott S., Greco, Edwin F., Lin, Shih-Yin, Schatz, Michael F., Thoms, Brian D.   +6 more
core   +1 more source