Results 71 to 80 of about 44,866 (295)

Public Awareness of the Scientific Consensus on Climate

open access: yesSAGE Open, 2016
Questions about climate change elicit some of the widest political divisions of any items on recent U.S. surveys. Severe polarization affects even basic questions about the reality of anthropogenic climate change (ACC), or whether most scientists agree ...
Lawrence C. Hamilton
doaj   +1 more source

Practical Considerations in Cloud Utilization for the Science Gateway nanoHUB.org

open access: yes, 2011
nanoHUB.org is arguably the largest online nanotechnology user facility in the world. Just between July 2010 and June 2011 it served 177,823 users. 10,477 users ran 393,648 simulation jobs on a variety of computational resources ranging from HUBzero ...
Smith, Preston M.   +6 more
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Wissenschaftliche Informationen aus einer Hand - Erfahrungen aus Kroatien / One-stop shop for scientific information - experiences from Croatia

open access: yesGMS Medizin – Bibliothek – Information, 2006
Since 1994 Croatian university and special libraries are working together in a project called Croatian Scientific Information System. Its intention is to develop various information services and to provide access to electronic resources for their patrons.
Stojanovski, Jadranka
doaj  

A synergistic workspace for human consciousness revealed by Integrated Information Decomposition

open access: yeseLife
How is the information-processing architecture of the human brain organised, and how does its organisation support consciousness? Here, we combine network science and a rigorous information-theoretic notion of synergy to delineate a ‘synergistic global ...
Andrea I Luppi   +13 more
doaj   +1 more source

Assessment of Natural Resources Use for Sustainable Development - DPSIR Framework for Case Studies in Portsmouth and Thames Gateway, U.K.

open access: yes, 2014
This chapter reports on the uses of the DPSIR framework to assess the sustainability of the intertidal environments within the two UK case study areas, Portsmouth and Thames Gateway.
L. Cedola   +13 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Smokeless tobacco, ENDS and harm reduction: ¿trick or treat?

open access: yesTobacco Prevention and Cessation, 2018
Introduction The harm reduction arises to reduce diseases related to tobacco or previous step to the abstinence. Historically, faced with the concern of its customers, the tobacco industry exploited this concept to promote cigarettes with filters, light ...
Jose Manuel Iglesias-Sanmartin   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy