Results 41 to 50 of about 13,766,818 (209)
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
ASSESSMENT FOR A CONDITION USING TERRESTRIAL LIDAR DATA [PDF]
The pothole is called a road breakage where the surface of road is locally recessed. The conventional vehicle-mounted pothole detection sensor acquires data only when the vehicle directly contacts the pothole and moreover, the acquired data is limited to
J. S. Park, K. S. Lee, S. Kim
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Overlap Between Lean Production and Scientific Management
Research question: Does the base of lean production include principles and factors of Taylor's scientific management? Purpose: The purpose of our research was to establish the value of overlap of the principles and factors of lean organization with ...
Izdriz Selimović, Mirko Markič
doaj
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
A Qualitative Study on Development of Enriching Performance Management System at a Pharma-Company [PDF]
This case study aimed to develop a sample of enriching the performance management system using qualitative method. The job post of Import Executive in a pharma company has been selected as a sample.
Hanif, Muhammad A.; Institute of Business Management, Karachi +2 more
core +3 more sources
Boston University School of Management Faculty profiles [PDF]
Profiles of Boston University School of Management faculty (1990/1991)
Boston University School of Management
core +1 more source
An economic assessment of population health risk in region [PDF]
This paper proposes a method of economic assessment of population health risk as a tool of life qualitymanagement and qualityof labor resources in the region (as factors of a region’s economic security).
Nina Vladimirovna Zaytseva +2 more
doaj +1 more source

