Results 51 to 60 of about 13,766,818 (209)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

The Design of Scientific Research Project Management System in Universities [PDF]

open access: yes, 2014
Researching and designing the university scientific research project management system based on network is conducive to tracking, guiding and managing product life-cycle of the whole research procedure management of projects.
QI, Xiaojuan, SUN, Shuyan, YANG, Yongji
core   +1 more source

Venture Labor| Making Media Work: Turning to Labor Management in Communication Studies

open access: yesInternational Journal of Communication, 2017
This essay discusses a work in progress that explores how new media technologies promised to manage labor. From the film technologies of the early 20th century to today’s smart mobile devices and algorithmic software, new media have been allied with ...
Michelle Rodino-Colocino
doaj  

Analysis of Issues Arising from Food Claims in the ''Functionalization Trend'' of the Food Market and Recommendations for Scientific Management

open access: yesShipin gongye ke-ji
As the people's health and wellness needs continue to grow, traditional dietary nutrition, medicinal diets and other "treatment of disease" concept is increasingly popular, with "food and medicine substances", new food raw materials such as raw materials,
Ming TIAN   +5 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Information systems management maturity and information technology security effectiveness [PDF]

open access: yes, 2004
vii, 129 leaves ; 29 cm.Modern societies rely on Information Systems (IS), yet their protection has long been considered ineffective. Researchers and practitioners have struggled to understand the persistence of this phenomenon, but both agree that IS ...
Spicer, Garry   +1 more
core  

Open Access to scientific knowledge: a methodological model for scientific information and knowledge management at the Brazilian Agricultural Research Corporation (Embrapa) [PDF]

open access: yes, 2008
This paper presents a methodological model for the establishment of Open Access to scientific information at Embrapa, as a strategy for scientific information and knowledge management. The model consists of elements that speed up scientific communication
Leite, Fernando César Lima   +2 more
core   +1 more source

El Cid: Can an Aesthetics Lens Save Transformational Leadership from Itself?

open access: yesEducation Sciences
Countless articles and books have been written about transformational leadership theory since the late 1970s when it first appeared in the literature. The purpose of this conceptual paper is to illustrate that transformational leadership contains both ...
Fenwick Walter English   +1 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Conflict management approaches, customer expectation evaluation, and customer satisfaction : an empirical investigation [PDF]

open access: yes, 2004
vii, 71 leaves ; 29 cm.This study investigates the potential impacts of different conflict management approaches and expectation evaluation on customer satisfaction.
University of Lethbridge. Faculty of Management   +1 more
core  

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