Results 91 to 100 of about 7,127,731 (257)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Mount Liebig, Northern Territory [cartographic material] : Commonwealth topographic survey /

open access: yes, 1960
Provisional ed. Topographic map of Mount Liebig region, Northern Territory, showing classes of roads, railway and telephone lines, mines, post offices, wireless transceivers, windpumps, airports or airfields and landing grounds, horizontal control points,
Australia. Division of National Mapping.
core  

The evolution and development of public administration digitalization: an international bibliometric analysis

open access: yesCogent Social Sciences
Assessing the state of the mapping level and prospects for digitalization of public administration in the global economy over the past 40 years through the implementation of bibliometric analysis.
Sholpan Smagulova   +3 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Frew River, Northern Territory [cartographic material] : Commonwealth topographic survey /

open access: yes, 1959
Provisional ed. Topographic map of Frew River region, Northern Territory, showing classes of roads, railway and telephone lines, mines, post offices, wireless transceivers, windpumps, airports or airfields and landing grounds, horizontal control points ...
Australia. Division of National Mapping.
core  

Exploring Marshall–Olkin Models Through Bibliometric and Topic Modeling Approaches Using Latent Dirichlet Allocation (1981–2025): A Study Based on Scopus Data

open access: yesMathematics
The Marshall–Olkin family of distributions has gained increasing attention in fields such as reliability engineering, survival analysis, financial risk modeling, and actuarial science because of its flexibility in modeling dependence among events and its
Humberto Llinás   +3 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Springvale, Queensland [cartographic material] : Commonwealth Topographic Survey /

open access: yes, 1961
Provisional ed. Topographic map of Springvale region, Queensland, showing classes of roads, railway and telephone lines, fences, state boundries, watercourses and dams, and windpumps.
Australia. Division of National Mapping.
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Review of flipped learning in engineering education: Scientific mapping and research horizon. [PDF]

open access: yesEduc Inf Technol (Dordr), 2022
Al Mamun MA   +3 more
europepmc   +1 more source

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