Results 81 to 90 of about 7,127,731 (257)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Tasmania 1:25 000 series [cartographic material] /

, 1979
Topographic map series with cadastral information. Relief shown by contours and spot heights. Depths shown by soundings.; "Tasmap."; Sheets of various eds.; Some sheets are issued by: Mapping Division, Department of Lands, Parks and Wildlife; Mapping ...
Tasmania. Lands Department Mapping Division.
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Ventilatörle İlişkili Pnömoniyi Önleme: Bibliyometrik Bir Çalışma

Yoğun Bakım Hemşireliği Dergisi
Amaç: Ventilatörle ilişkili pnömoniyi önleme üzerine yapılan araştırmaların bibliyometrik analizini incelemektir. Yöntem: Veriler, Nisan 2024 tarihinde “Web of Science (WoS) Core Collection” veri tabanından toplandı ve VOSviewer, R Studio 4.3.3 programı ...
Duygu Kes
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Tennant Creek, Northern Territory [cartographic material] : Commonwealth topographic survey /

, 1958
1st ed. Topographic map of Tennant Creek region, Northern Territory showing classes of roads, railway and telephone lines, mines, post offices, wireless transceivers, windpumps, airports or airfields and landing grounds, horizontal control points ...
Australia. Division of National Mapping.
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Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Tobermory, Northern Territory [cartographic material] : Commonwealth topographic survey /

, 1960
Provisional ed. Topographic map of Tobermorey region, Northern Territory, on sheet entitled Tobermory, Northern Territory, showing classes of roads, railway and telephone lines, mines, post offices, wireless transceivers, windpumps, airports or airfields
Australia. Division of National Mapping.
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Digital technologies in the classrooms in the last decade (2014–2023): a bibliometric analysis

Frontiers in Education
IntroductionDigital technologies are widely integrated with teaching and learning, and examining these technological interventions in the classrooms has become an active research area.
Talha Mahboob Alam, George Adrian Stoica, Kshitij Sharma, Özlem Özgöbek   +3 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Photo index ... New Guinea [cartographic material].

, 1956
Photomosaic series of Papua New Guinea.; "This photo index is merely a copy of an assembly of air photographs and is not an accurate map."; "Names shown in red on this map have been supplied by C.S.I.R.O. Land Research Unit and are subject to approval by
Australia. Division of National Mapping.
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