Results 131 to 140 of about 1,497,668 (296)
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Mapping the transition from arithmetic to algebra: a bibliometric and structural review (2003–2023)
Frontiers in EducationThe shift from arithmetic to algebra entails significant cognitive and pedagogical challenges for both students and teachers. Despite its importance in early mathematics education, few systematic reviews have comprehensively examined the scientific ...
Victoria Alejandra García Fajardo +2 more
doaj +1 more source
Global Trends in Cancer Nanotechnology: A Qualitative Scientific Mapping Using Content-Based and Bibliometric Features for Machine Learning Text Classification. [PDF]
Cancers (Basel), 2021 Millagaha Gedara NI +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Apollo 17 mission. Mapping camera extension mechanism operated erratically [PDF]
The erratic operation of the mapping camera assemblies on board Apollo 15, 16, 17 is investigated. The exact causes of the problems with the scientific equipment module deployment mechanisms are not identified.
core +1 more source
Diverging Color Maps for Scientific Visualization
, 2009 One of the most fundamental features of scientific visualization is the process of mapping scalar values to colors. This process allows us to view scalar fields by coloring surfaces and volumes. Unfortunately, the majority of scientific visualization tools still use a color map that is famous for its ineffectiveness: the rainbow color map.
openaire +2 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Making Sense of Proprioception by Bibliometric Research
Brain and BehaviorBackground Proprioception is one of the most significant factors in balance, stability, fine movements, coordination, and injury prevention. Proprioception research helps clarify how the nervous system integrates sensory inputs to plan and execute ...
Kevser Sevik Kacmaz
doaj +1 more source