Results 61 to 70 of about 18,383,772 (292)
Beyond Kuhnian paradigms: Normal science and theory dependence in ecology
Ecology and Evolution, 2023 The Structure of Scientific Revolutions by Thomas Kuhn has influenced scientists for decades. It focuses on a progression of science involving periodic, fundamental shifts—revolutions—from one existing paradigm to another.
Craig A. Layman, Andrew L. Rypel
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Hawaii Scientific Drilling Project 1993 [PDF]
, 1994 Content: Project Summary, History of Hawaii Project, Permit History, Continental Scientific Drilling Office's Role, Setup and Coring of Kahi Puka Site, Downhole Problems, Cures for Problems, Conclusions, Appendices: Correspondence for Increase in Depth ...
core +3 more sources
Some Philosophical Problems of Studying Complex Systems in the Universe
Дискурс, 2020 Introduction. The paper deals with the philosophical problems of functioning of the most complex phenomena in the universe: creation of the universe, emergence of life and appearance of consciousness.
A. V. Nesteruk, A. V. Soldatov
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Method validation on iron determination by spectrophotometric method in aqueous medium [PDF]
, 2020 This paper deals with the validation of a method for the determination of iron in spectrophotometric method in aqueous medium. The method is based on complex formation of iron with thioglycolic acid (TGA) in alkaline medium in presence of a masking agent
Neger, Tahuran ; Bangladesh Council of Scientific and Industrial Research (BCSIR) +4 more
core +4 more sources
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Noxious stimulation induces self-protective behavior in bumblebees
iScienceSummary: It has been widely stated that insects do not show self-protective behavior toward noxiously-stimulated body parts, but this claim has never been empirically tested.
Matilda Gibbons +8 more
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We Need to Recreate Natural Philosophy
Philosophies, 2018 Modern science began as natural philosophy, an admixture of philosophy and science. It was then killed off by Newton, as a result of his claim to have derived his law of gravitation from the phenomena by induction.
Nicholas Maxwell
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The Speculative Method: Scientific Guesswork and Narrative as Laboratory
, 2021 In this chapter, I discuss two influences shaping what I call 'the speculative method' in biography. As a historian who writes about past lives, I take as my starting point the idea of 'history's doubleness', which Ann Curthoys and John Docker coined in ...
Lindsey, Kiera, Kiera Lindsey
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