Results 81 to 90 of about 18,383,772 (292)
Scientific literacy for sustainability [PDF]
, 2006 We only need to consider public media reports to appreciate that there is growing concern amongst citizens for sustainability. This concern arises from increasing appreciation that the current direction and rate of exploitation of resources is not ...
Murcia, Karen
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
The methodology of natural sciences in antiquity and the second book of Galen’s De placitis Hippocratis et Platonis [PDF]
SCHOLE, 2015 In this article, based on the second book of Galen’s De placitis Hippocratis et Platonis, we analyze scientific method of the famous anatomist and philosopher.
Koptseva, Natalia +2 more
doaj
METHODOLOGY IN SCIENCE AND RELIGION: A REPLY TO CRITICS
Zygon, 2020 Debates about methodology have been central to the emergence of the “field of science of religion.” Two questions that have motivated scholars in that field over the past half century: “is it theoretically justifiable to bring scientific and religious ...
doaj +2 more sources
Scientific integrity in research methods [PDF]
Frontiers in Psychology, 2015 Recent cases of research misconduct have prompted psychologists to suggest that there is too much vulnerability in the research process (e.g., Simmons et al., 2011; Pashler and Harris, 2012). Regardless of whether this is the case, ensuring the integrity of a discipline requires a clear understanding of what conventions and norms define the research ...
openaire +3 more sources
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Approximate Inference and Scientific Method
Information and Computation, 1994 AbstractA new identification criterion, motivated by notions of successively improving approximations in the philosophy of science, is defined. It shown that the class of recursive functions is identifiable under this criterion. This result is extended to apply to somewhat more realistic types of data than usual.
Mark A. Fulk, Sanjay Jain 0001
openaire +3 more sources
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source