Results 61 to 70 of about 20,029,027 (295)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
"Methods": A new type of articles to be published in the OAJ Materials and Devices
Materials and Devices, 2022 Brief description of the new type of article accepted in the Open Access journal "Materials and Devices": Methods.
Pierre Saint Gregoire
doaj +6 more sources
Soil SystemsMicroorganisms are fundamental drivers of soil productivity, mediating nutrient cycling and pathogen suppression. In this study, we evaluated changes in the fungal community in the soil of barley (Hordeum vulgare L.) in a field experiment involving the ...
Roderic Gilles Claret Diabankana +9 more
doaj +1 more source
Геофизический журнал, 2011 The results of the CDP, DSS, ECWM regional seismic and seismotomographic study of the Onega-Ladoga area, conducted in 1975-2002, are reviewed. Combined multi-wave studies are carried out to reveal the essential details of the deep structure of the earth ...
N. V. Sharov +4 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
A Universal Method of Scientific Inquiry [PDF]
Machine Learning, 1992 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Daniel N. Osherson +2 more
openaire +3 more sources
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
The algorithms for automated calculation of the furnace charge in smelting and refining metal [PDF]
Trudy Odesskogo Politehničeskogo Universiteta, 2017 The production of the initial liquid metal with minimal departures from the regulated chemical composition is one of the main conditions for the production of high-quality castings with predetermined physical, mechanical and operational properties.
Kungurtsev Аlexey B. +3 more
doaj +1 more source