Results 31 to 40 of about 166,748 (266)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
مجله علمسنجی کاسپین, 2018 Background and aim: The aim of this study was to understand, acknowledge and assess the scientific outputs in order to compare the scientific map of Iran with the global scientific map so that we could identify the interdisciplinary fields and make ...
Mohammad Bagher Negahban +1 more
doaj
Evaluating the scientific outputs of information management researchers in WoS [PDF]
مجله علمسنجی کاسپین, 2019 Background and aim: The scientometrics are one of the most efficient methods of evaluating scientific outputs. The aim of the present study was to investigate the scientific outputs of all information management researchers in the Web of Science (WoS) in
Sholeh Zakiani +2 more
doaj
Drawing and analyzing the world\'s scientific collaboration network in the field of crisis management [PDF]
مجله علمسنجی کاسپین, 2021 Background and aim: The aim of this study was to draw and analyze the world's scientific collaboration in the field of crisis management based on data retrieved from the Web of Science (WoS).
Farideh Osareh +2 more
doaj
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
A Multidimensional Framework for Measuring Scientific Leadership
International Journal of Information Science and Management, 2022 Scientific progress has been one of the critical concerns of many nations in recent decades. It has become one of the top priorities at the highest policy-making levels in several countries.
Ghasem Azadi Ahmadabadi, Behrooz Rasuli
doaj
Analyzing Scientific Outputs of Qom University Emphasizing Co-authorship of Researchers [PDF]
مجله علمسنجی کاسپین, 2021 Background and aim: For any progress, countries need scientific outputs, and that is only possible through research. Therefore, the aim of this study was to analyze the status of scientific outputs of Qom University in the Web of Science (WoS ...
Zahra Zamani, Fatemeh Maleki Borjeloo
doaj
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source