Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Qualitative evaluation of research activities using the same keywords
Background and aim: Various scientometric indicators have been developed for quantitative and qualitative evaluation of scientific output. Each of these indicators has its own weaknesses and strengths.
Aram Tirgar +2 more
doaj
Investigating the Application of serial Publications in scientific Output of Faculty Members in Human Sciences Departments of Shiraz University during 1998 and 2007 [PDF]
The present study aims to determine and investigate the contribution of serial publications in scientific output of faculty members in human sciences departments (departments of Literature and Human Sciences, Educational Sciences, Social Sciences ...
Fatemeh Fahimnia, Fatemeh Jaafari
doaj
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Scientific outputs of the medical sciences faculty members of the Shahed University in Scopus citation database (2000–2011) [PDF]
Purpose: The present research was performed for exploring of scientific outputs of Shahed University medical sciences faculty members in Scopus citation database (2000-2011).
Javad Riahi Asl, Ali Sharafi
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Tracing the Scientific Status of Researchers Outputs in the Field of Parasitology as Reflected in Science Citation Databases [PDF]
Background & Objective: The purpose of the present study is to trace the scientific status of researchers outputs in the field of parasitology as reflected in science citation databases during 19952010 Methods: In this study outputs of researchers in the
Leila Namdar +2 more
doaj
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Ranking the Scientific Output of Researchers in Fractional Calculus [PDF]
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Tenreiro Machado, J. A. +1 more
openaire +2 more sources
Exploring Scientific Outputs about Globalization: A Conceptual Framework Study [PDF]
IntroductionBibliometric analysis is widely acknowledged as a robust and systematic approach for examining extensive scholarly literature. It serves as a vital tool for mapping the landscape of contemporary research across various academic fields.
Saleh Rahimi, Faramarz Soheili
doaj +1 more source

