Results 51 to 60 of about 442,839 (286)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Interactive PnP Innovation For Muamalat Diploma Students' Final Year Project

open access: yesMalaysia Journal of Invention and Innovation, 2023
The Scientific paper is a required subject for final year Muamalat Diploma students at UiTMCTKD in semester 5. The Wheel of Fortune Interactive PnP Innovation Project (PWoFKi) method is used to assess students' comprehension of input for writing a ...
Nor Adila Mohd Noor   +4 more
doaj   +2 more sources

Analisis Sitiran Karya Ilmiah Pustakawan Indonesia pada Jurnal Visi Pustaka Tahun 2008-2013

open access: yesBerkala Ilmu Perpustakaan dan Informasi, 2016
The study aims: (1) to discover the scientific paper librarians referred by the Visi Pustaka Journal in 2008-2013, (2) to know the percentage of use of the subscribed the scientific paper librarians, (3) to know the relevancy and use of scientific paper ...
Sri Junandi
doaj   +1 more source

Research on Scientific Journals: Implications for Editors and Authors [PDF]

open access: yes
A review of editorial policies of leading journals and of research relevant to scientific journals revealed conflicts between 'science' and 'scientists.” Owing to these conflicts, papers are often weak on objectivity and replicability.
JS Armstrong
core  

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

The importance in the papers' impact of the number of pages and of co-authors - an empirical estimation with data from top ranking economic journals [PDF]

open access: yes
On a regular basis the scientific output of academic people has to be evaluated, e.g. to decide tenure. A very important item in this evaluation is the published papers’ quality that tends to be approximated by its impact in the literature.
Pedro Cosme Costa Vieira
core  

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

open access: yesFEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara   +3 more
wiley   +1 more source

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