Results 161 to 170 of about 1,135,884 (299)

Geography of Scientific Knowledge: A Proximity Approach [PDF]

open access: yes
The geography of scientific knowledge is defined as the replication process of locally produced knowledge claims. Proximity in social, cognitive, and physical dimensions promotes the sharing of tacit knowledge.
Koen Frenken
core  

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Person-centred care and evidence-informed practice

open access: yes
Invited keynote speaker, “Person-centred care and evidence-informed practice,” Winter summit of the European Academy of Nursing Science: What is the relationship between Person-Centred Healthare and Evidence-Informed Practice? Historically, there has
Loughlin, Michael
core  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Reply to Krefeld-Schwalb et al.: Measuring population heterogeneity requires upholding good scientific practice. [PDF]

open access: yesProc Natl Acad Sci U S A
Holzmeister F   +5 more
europepmc   +1 more source

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