Results 31 to 40 of about 165,436 (245)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

La Unió Europea com a cap i garant del sistema d'avaluació i difusió de la producció científica

open access: yesBiD: Textos Universitaris de Biblioteconomia i Documentació, 2019
Es presenta i es desenvolupa un sistema potencial d'avaluació i difusió de l'activitat científica generada a partir de recursos de finançament públics.
Caldera Serrano, Jorge
doaj   +1 more source

The effect of Open Access on scientometric indicators of Russian economic journals

open access: yesУправленец, 2022
Numerous publishers view the Open Access (OA) model as one of the ways to strengthen journals’ position. Enhancing the visibility of publications is believed to increase research productivity.
Olga A. Chernova
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

PRINCIPLES OF DESCRIBING THE AESTHETIC CHARACTERISTICS OF NATURAL LANDSCAPES

open access: yesВопросы лесной науки
The possibilities of quantitative assessment of aesthetic services of natural landscape in forests and parks are considered. An attempt to «weigh» the quality of aesthetic services and aesthetic properties of different landscapes is discussed.
A. G. Soukhovolsky   +4 more
doaj   +1 more source

La Unión Europea como cabecera y garante del sistema de evaluación y difusión de la producción científica

open access: yesBiD: Textos Universitaris de Biblioteconomia i Documentació, 2019
Se presenta y desarrolla un potencial sistema de evaluación y difusión de la actividad científica generada a partir de recursos de financiación públicos.
Caldera Serrano, Jorge
doaj   +1 more source

Digital identifiers for researchers and their impact on scientific productivity: the case of ORCID

open access: yesCybrarians Journal, 2023
Accurate identification of researchers and their scientific output is crucial for all parties involved in scientific research (such as publishers, funders, and universities), as many processes like promotions, securing funding, publishing, and article ...
Tasneem Ali
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

The Price of Precision: A Critical Review of Molecular Diagnostics in Glioma, From Guidelines to Global Disparities

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
wiley   +1 more source

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