Results 31 to 40 of about 165,436 (245)
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
La Unió Europea com a cap i garant del sistema d'avaluació i difusió de la producció científica
Es presenta i es desenvolupa un sistema potencial d'avaluació i difusió de l'activitat científica generada a partir de recursos de finançament públics.
Caldera Serrano, Jorge
doaj +1 more source
The effect of Open Access on scientometric indicators of Russian economic journals
Numerous publishers view the Open Access (OA) model as one of the ways to strengthen journals’ position. Enhancing the visibility of publications is believed to increase research productivity.
Olga A. Chernova
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
PRINCIPLES OF DESCRIBING THE AESTHETIC CHARACTERISTICS OF NATURAL LANDSCAPES
The possibilities of quantitative assessment of aesthetic services of natural landscape in forests and parks are considered. An attempt to «weigh» the quality of aesthetic services and aesthetic properties of different landscapes is discussed.
A. G. Soukhovolsky +4 more
doaj +1 more source
Se presenta y desarrolla un potencial sistema de evaluación y difusión de la actividad científica generada a partir de recursos de financiación públicos.
Caldera Serrano, Jorge
doaj +1 more source
Digital identifiers for researchers and their impact on scientific productivity: the case of ORCID
Accurate identification of researchers and their scientific output is crucial for all parties involved in scientific research (such as publishers, funders, and universities), as many processes like promotions, securing funding, publishing, and article ...
Tasneem Ali
doaj +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
wiley +1 more source

