Results 41 to 50 of about 638,395 (262)

Editorial independence and scientific publications

Neurología (English Edition), 2010
Introduction: Various cases of editors of leading journals resigning have led to a debate on the question of editorial independence, understood as the unconditional freedom of editors to approve the contents of their journals. Method: An analysis is made
J. Matías-Guiu, R. García-Ramos
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Produção científica de 10 anos da revista Psicologia Escolar e Educacional (1996/2005)

Psicologia Escolar e Educacional
Esta pesquisa visou investigar a produção científica de dez anos de publicações da Psicologia Escolar e Educacional. A análise baseou-se em alguns critérios da metaciência, a saber, autoria, temática, discurso e análise dos tipos de avaliações.
Katya Luciane Oliveira, Lucicleide Maria de Cantalice, Maria Cristina Rodrigues Azevedo Joly, Acácia Aparecida Angeli dos Santos   +3 more
doaj   +1 more source

Editorial bias in scientific publications

Neurología (English Edition), 2011
Introduction: Many authors believe that there are biases in scientific publications. Editorial biases include publication bias; which refers to those situations where the results influence the editor's decision, and editorial bias refers to those ...
J. Matías-Guiu, R. García-Ramos
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

[Challenge in scientific publication].

Pesquisa odontologica brasileira = Brazilian oral research, 2003
We discuss the main problems which make a scientific text difficult to find, to be read or to be accepted by readers. A scientific text is considered a logical argument. Therefore, methods, results and data from literature are premises supporting the conclusions of the work; and in the "Introduction" session, the justification corroborates the ...
Volpato, Gilson Luiz, Freitas, Eliane Gonçalves de   +1 more
openaire   +2 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

The flexibility of Islamic architecture (the architecture of the 19th century in Cairo as a model)

Journal of Architecture, Art & Humanistic Science, 2017
بخروج الحملة الفرنسیة من مصر سنة 1218 هـ / 1803م بعد ان استمرت ثلاث سنوات بدأ عهد جدید من الانفتاح على الثقافة الأوربیة والغربیة فى مصر فعلی الرغم من أن مصر کانت لا تزال متأثرة بالطراز المعماری والفنی الذی ساد فى العصر العثمانی وتأثر الطرز المعماریة ...
Yasser Ali, Amal Ahmed
doaj   +1 more source