Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Produção científica de 10 anos da revista Psicologia Escolar e Educacional (1996/2005)
Psicologia Escolar e EducacionalEsta pesquisa visou investigar a produção científica de dez anos de publicações da Psicologia Escolar e Educacional. A análise baseou-se em alguns critérios da metaciência, a saber, autoria, temática, discurso e análise dos tipos de avaliações.
Katya Luciane Oliveira +3 more
doaj +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Analyzing Citation-Distance Networks for Evaluating Publication Impact [PDF]
, 2018 Studying citation patterns of scholarly articles has been of interest to many researchers from various disciplines. While the relationship of citations and scientific impact has been widely studied in the literature, in this paper we develop the idea of ...
Herrmannova, Drahomira +2 more
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Can We Count on Social Media Metrics? First Insights into the Active Scholarly Use of Social Media
, 2018 Measuring research impact is important for ranking publications in academic search engines and for research evaluation. Social media metrics or altmetrics measure the impact of scientific work based on social media activity.
Kling, Christoph Carl +4 more
core +1 more source
Scientific Publication Patterns of Mobile Technologies and Apps for Posttraumatic Stress Disorder Treatment: Bibliometric Co-Word Analysis [PDF]
, 2020 Atık Kulakli, Ivanna Shubina
openalex +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
The flexibility of Islamic architecture (the architecture of the 19th century in Cairo as a model)
Journal of Architecture, Art & Humanistic Science, 2017 بخروج الحملة الفرنسیة من مصر سنة 1218 هـ / 1803م بعد ان استمرت ثلاث سنوات بدأ عهد جدید من الانفتاح على الثقافة الأوربیة والغربیة فى مصر فعلی الرغم من أن مصر کانت لا تزال متأثرة بالطراز المعماری والفنی الذی ساد فى العصر العثمانی وتأثر الطرز المعماریة ...
Yasser Ali, Amal Ahmed
doaj +1 more source
NASA scientific and technical publications: A catalog of special publications, reference publications, conference publications, and technical papers, 1989 [PDF]
This catalog lists 190 citations of all NASA Special Publications, NASA Reference Publications, NASA Conference Publications, and NASA Technical Papers that were entered into the NASA scientific and technical information database during accession year ...
core +1 more source