Results 41 to 50 of about 252,676 (294)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa +3 more
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Selective Realism vs. Individual Realism for Scientific Creativity [PDF]
, 2017 Individual realism asserts that our best scientific theories are (approximately) true. In contrast, selective realism asserts that only the stable posits of our best scientific theories are true.
Park, Seungbae
core +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
RUDN Journal of Studies in Literature and Journalism, 2019 There are many terms that denote the invasion of the inexplicable into a realistic narrative, such as: magical realism, fantastic realism, mystical realism, spiritual realism, transcendental realism, metaphysical realism, Christian realism, etc.
Vitaliy Alexandrovich Gavrikov
doaj +1 more source
The Role of Existential Quantification in Scientific Realism [PDF]
, 2017 Scientific realism holds that the terms in our scientific theories refer and that we should believe in their existence. This presupposes a certain understanding of quantification, namely that it is ontologically committing, which I challenge in this ...
Finn, Suki
core +2 more sources
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Practical Realism: Against Standard Scientific Realism and Anti-Realism
Studia Philosophica Estonica, 2012 In this paper, the elaboration of the concept of practical realist philosophy of science which began in the author's previous papers is continued.
Rein Vihalemm
doaj
, 2013 This paper proposes to carve out a new position in the scientific realism/antirealism debate and argue that it captures some of the most important realist and some of the most important antirealist considerations.
Nanay, Bence
core +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source