Results 51 to 60 of about 5,759,774 (291)
Scientific Realism, the Galilean Strategy, and Representation [PDF]
, 2009 This paper critically reviews Philip Kitcher’s most recent epistemology of science, real realism. I argue that this view is unstable under different understandings of the term “representation”, and that the arguments offered for the position are either ...
Suárez, Mauricio
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RUDN Journal of Studies in Literature and Journalism, 2019 There are many terms that denote the invasion of the inexplicable into a realistic narrative, such as: magical realism, fantastic realism, mystical realism, spiritual realism, transcendental realism, metaphysical realism, Christian realism, etc.
Vitaliy Alexandrovich Gavrikov
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Humean Perspectives on Structural Realism [PDF]
, 2009 The paper is a kind of opinionated review paper on current issues in the debate about Structural Realism, roughly the view that we should be committed in the structural rather than object-like content of our best current scientific theories.
Lyre, Holger
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Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
KITCHER’S MODEST REALISM: THE RECONCEPTUALIZATION OF SCIENTIFIC OBJECTIVITY [PDF]
, 2010 In Science, Truth and Democracy, Kitcher moderates the strongest ontological realist thesis he defended in The Advancement of Science, with the aim of making compatible the correspondence theory of truth with conceptual relativity.
Dieguez, Antonio
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Scientific realism and underdetermination in quantum theory [PDF]
, 2021 This paper surveys the status of scientific realism in relation to quantum physics, focusing on the problem of ...
Egg, Matthias +5 more
core +2 more sources
The Fertility of Theories [PDF]
, 2009 In addition to empirical adequacy and compatibility with other current theories, scientific theories are commonly judged on three criteria ' simplicity, elegance, and fertility.
Segall, Robert
core +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Is There a Compelling Argument for Ontic Structural Realism? [PDF]
, 2011 Structural realism first emerged as an epistemological thesis aimed to avoid the so-called pessimistic meta-induction on the history of science. Some authors, however, suggested that the preservation of structure across theory-change is best explained by
Morganti, Matteo
core +1 more source