Results 181 to 190 of about 2,993,514 (349)

Newsletter of the National Caucus of Chicano Social Scientists, vol. 1, no. 1, Summer 1973 [PDF]

, 1973
National Caucus of Chicano Social Scientists
core   +1 more source

Modeling Scientists as Agents. How Scientists Cope with the Challenges of the New Public Management of Science [PDF]

The paper at hand applies agent-based modeling and simulations (ABMS) as a tool to reconstruct and to analyze how the science system works. A Luhmannian systems perspective is combined with a model of decision making of individual actors.
Johannes Weyer, Marc M�lders, Robin D. Fink   +2 more
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Critical actions for embedding research evidence into practice: how to get the most out of your implementation scientist. [PDF]

JBI Evid Implement
Mazariego C, Gul H, Liang S, Kelly-Hanku A, Brady B, Allida S, Baffsky R, McErlean G, Crespo C, Hodgins M, Christie L, Peiris D, Debono D, MacMillan F, Ferguson C, Heneka N, Kennedy SG, Liu H, Morrow A, Fontaine G, Findlay M, Middleton S, Lim D, Straiton N, Taylor N.   +24 more
europepmc   +1 more source

Citizen scientists [PDF]

Nature, 2010
openaire   +2 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

The Tenuous Future of Our Next Generation of Physician-Scientists. [PDF]

ATS Sch
Schwartz DA.
europepmc   +1 more source

Singular Scientists [PDF]

Journal of the Royal Society of Medicine, 2003
openaire   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

When learning becomes doing: contributions of the next generation of scientists to knowledge about genetics and genomics. [PDF]

G3 (Bethesda)
McIntyre LM.
europepmc   +1 more source