Results 201 to 210 of about 495,623 (265)

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Cardiovascular Health and Financial Hardship: Protocol for a Qualitative Citizen Science Study. [PDF]

JMIR Res Protoc
Niewold D, van Gestel ECE, Abidi L, Tiemstra K, Thoolen M, Nagelhout GE.   +5 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Retracted Randomized Clinical Trials From Superretractors and Top-Cited Scientists With Multiple Retractions.

JAMA Netw Open
Lyu C, Matbouriahi M, Naudet F, Ioannidis JPA, Cristea IA.   +4 more
europepmc   +1 more source

Otolaryngology Surgeon-Scientists: The Road Less Traveled. [PDF]

OTO Open
Aaron T, Haung J, Prasad S, Krishnan PS, Forman G, Wolf L, Sokhn E, Kring T, Souza B, Dinh CT, Franzmann EJ, Liu XZ.   +11 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Correction: Funding in "It Is Time for Physician-Scientists to Lead Their Own Development". [PDF]

J Korean Med Sci
Lee DH, Kim JI.
europepmc   +1 more source

Worms About Town: a citizen science project discovers microsporidian parasites of nematodes through environmental sampling. [PDF]

Biol Open
Tersigni J, James EB, Reinke AW.
europepmc   +1 more source

Methodological Considerations Regarding Diuretic Intensity Score and Mortality in Hospitalized Heart Failure Patients. [PDF]

Clin Cardiol
Haider NU, Khan UA, Saleem L, Khan M, Fayaz MH.   +4 more
europepmc   +1 more source