Results 101 to 110 of about 1,632,227 (336)

Exploration of structure–activity relationship of 2,4‐diaminopyrimidine derivatives as hematopoietic progenitor kinase 1 inhibitors

open access: yesBulletin of the Korean Chemical Society, EarlyView.
Targeting HPK1 is a promising strategy to restore T‐cell anti‐tumor immunity. We report the design and synthesis of novel 2,4‐diaminopyrimidine derivatives, focusing on systematic structure–activity relationship (SAR) analysis These findings identify key structural features for potent HPK1 inhibition, facilitating the discovery of next‐generation ...
Heechan Shin   +3 more
wiley   +1 more source

Radioassay by gas-liquid chromatography of lipids labeled with carbon-14

open access: yesJournal of Lipid Research, 1962
A method for radioassay of carbon-I4 labeled substances analyzed by gas-liquid chromatography is described. The column effluent is automatically fractionated by condensing the vapor in a series of cartridges filled with anthracene crystals coated with ...
Arthur Karmen   +2 more
doaj   +1 more source

Nanofiber PVA‐Based Membranes Incorporating Functionalized Spanish Broom Derivatives for Sustainable Water Purification

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This study investigates Spanish broom (Spartium junceum) as a renewable source for electrospun composite membranes in sustainable water purification. MCC and biochar were functionalized with eco‐friendly precursors and nanomaterials (i.e., HNT, β‐CDs) to develop hybrid PVA nanofiber composites.
Giulia Rando   +7 more
wiley   +1 more source

Liquid Scintillation Counting [Elektronisk resurs]

open access: yes, 1993
In liquid scintillation counting (LSC) we use the process of luminescense to detect ionising radiation emit$ed from a radionuclide. Luminescense is emission of visible light of nonthermal origin.
Carlsson, Sten,
core  

Flexible Direct‐Conversion X‐Ray Detectors: From Emerging Materials to Conformal Imaging

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This comprehensive review analyzed the performance, challenges, and future directions of four emerging material systems for next‐generation flexible direct‐conversion X‐ray detectors: organic semiconductors, perovskites, metal–organic frameworks, and inorganic metal compounds.
Haipeng Di   +11 more
wiley   +1 more source

Standardization of alpha-emitters by liquid-scintillation counting

open access: yes, 1966
Internal liquid scintillation counting allows a high precision in the standardization of solutions of $\alpha$-emitting nuclides. The method has a number of advantages: under appropriate experimental conditions, a 4$\pi$ geometry is obtained; the ...
Murrenhoff, A. P.   +2 more
core  

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang   +7 more
wiley   +1 more source

Use of a filter-paper disk assay in the measurement of lipid biosynthesis

open access: yesJournal of Lipid Research, 1966
The precipitation by trichloroacetic acid (TCA) of radioactive lipids on disks of filter-paper, followed by extraction with TCA and water to remove soluble radioactive precursors, provides the means for a convenient assay for lipid biosynthesis.
Howard Goldfine
doaj   +1 more source

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