Results 31 to 40 of about 57,365 (255)

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Microstructural Evolution and Vacancy Defect Formation in Mn–Mo–Ni RPV Steel Under Low Cycle Fatigue: Insights From EBSD and PALS

Advanced Engineering Materials, EarlyView.
Low‐cycle fatigue damage in Mn–Mo–Ni reactor pressure vessel steel is examined using a combined electron backscatter diffraction and positron annihilation lifetime spectroscopy approach. The study correlates texture evolution, dislocation substructure development, and vacancy‐type defect formation across uniform, necked, and fracture regions, providing
Apu Sarkar, Dhanadeep Dutta, G. Bharat Reddy   +2 more
wiley   +1 more source

Comparison of Image Uniformity with Photon Counting and Conventional Scintillation Single-Photon Emission Computed Tomography System: A Monte Carlo Simulation Study

Nuclear Engineering and Technology, 2017
To avoid imaging artifacts and interpretation mistakes, an improvement of the uniformity in gamma camera systems is a very important point. We can expect excellent uniformity using cadmium zinc telluride (CZT) photon counting detector (PCD) because of ...
Ho Chul Kim, Hee-Joung Kim, Kyuseok Kim, Min-Hee Lee, Youngjin Lee   +4 more
doaj   +1 more source

From Sintering to Particle Discrimination: New Opportunities in Metal–Organic Frameworks Scintillators

Advanced Photonics Research, 2022
The characterization of a scintillating metal organic framework (MOF) is not straightforward, mainly due to the small size and low density of the material. In this context, we present herein a generic method to give an easy access to the determination of
Vincent Villemot, Nicolas Dufour, Sharvanee Mauree, Benoît Sabot, Guillaume H. V. Bertrand, Matthieu Hamel   +5 more
doaj   +1 more source

Glissile Interphase Boundaries Enable Collective Phase Switching in Epitaxial Polar Oxides

Advanced Functional Materials, EarlyView.
A triple point is identified in the phase diagram of low‐symmetry epitaxial BiFeO3 thin film along with an extended regime of phase competition associated with a flattened energy landscape. The electromechanical response is shown to be governed by correlated interphase‐boundary motion, including scale‐free avalanche dynamics characteristic of systems ...
Mohammad Moein Seyfouri, Oliver Paull, Ralph Bulanadi, Yasuhiro Sakamoto, Shintaro Yasui, Mikayla Lord, Mahak Chhabra, David Walker, Patrycja Paruch, Shery Chang, Nagarajan Valanoor, Daniel Sando   +11 more
wiley   +1 more source

Comparison of the efficacy of biodegradable and non-biodegradable scintillation liquids on the counting of tritium- and [14C]-labeled compounds

Brazilian Journal of Medical and Biological Research, 2003
The widespread use of ³H and 14C in research has generated a large volume of waste mixed with scintillation liquid, requiring an effective control and appropriate storage of liquid radioactive waste.
Medeiros R.B., Godinho R.O., Mattos M.F.S.S.   +2 more
doaj  

Absolute Measurement of Alpha Radioactivity and Elemental Amount of Substance Using Liquid Scintillation Method

Yuanzineng kexue jishu
The liquid scintillation counting method is a simple technique for the absolute activity measurement of α particles. However, it is less common in analytical applications than might be expected.
FENG Xiaogui, YUAN Jianhua, HE Qiange, SUN Taoxiang, WANG Jianchen, CHEN Jing
doaj   +1 more source

Advances in Halide Perovskites for Photon Radiation Detectors

Advanced Materials Technologies, EarlyView.
This work highlights recent progress in perovskite‐based photon radiation detectors, covering organic–inorganic hybrid, inorganic, lead‐free double, and vacancy‐ordered halide perovskites. Their detection performance is compared, material‐specific advantages and challenges are examined, and provides insight into current limitations and future ...
Liangling Wang, Jieqi Wang, Xiaojun Cui, Carsten Ronning   +3 more
wiley   +1 more source

Effect of Scintillation Cocktail and Quenching Calibration Method on Measurement of 55Fe by LSC

He huaxue yu fangshe huaxue
In order to optimize the measurement conditions of 55Fe by liquid scintillation counting, the effect of three kinds of commercial scintillation cocktail and two efficiency correction methods on LSC measurements of 55Fe was tested.
MA Li-na, DAI Xiong-xin, ZHANG Hui, MA Yan, SONG Li-juan   +4 more
doaj   +1 more source

Lead‐Free Chiral Hybrid Metal Halides for Circularly Polarized Light‐Emitting Diodes

Advanced Optical Materials, EarlyView.
Lead‐free chiral hybrid metal halides provide a versatile platform for realizing chiroptical responses through chiral modulation of metal–halide frameworks with diverse dimensionalities, induces inversion‐symmetry breaking and enables dissymmetric excited‐state transitions toward efficient circularly polarized luminescence and electroluminescence. This
Kun Zhu, Li Wan
wiley   +1 more source