Results 111 to 120 of about 38,036 (236)

PD‐L1 Promotes Immunological Tolerance and Enhances Visual Protection of hESC‐RPE Grafts in Retinal Degeneration

open access: yesCell Proliferation, EarlyView.
We generated immune‐tolerant mature hESC‐RPE cells by overexpressing PD‐L1. PD‐L1‐expressing hESC‐RPE grafts exhibited significantly higher survival, reduced apoptosis and enhanced visual protection in retinal degeneration models, which presents an alternative target to improve the efficiency of hESC‐RPE‐based therapy for AMD. ABSTRACT Immune rejection
Bowen Li   +11 more
wiley   +1 more source

Age ultrastructural features of sclera in intact rats [PDF]

open access: yesМорфологія, 2013
Background. The absence of adequate experimental myopia model is the actual problem in pathophysiological studying of the myopia progression. Studies of the chick eye have formed the basis for several hypotheses of myopic development.
Ulyanova N.A.   +2 more
doaj  

Objective assessment of acute pain in foals using a facial expression‐based pain scale

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Pain assessment based on facial expressions has been described in foals. Objectives To extend previous pilot findings of the Equine Utrecht University Scale for Facial Assessment of Pain in Foals (EQUUS‐FAP FOAL). Study design Prospective blinded case–control study (known groups analysis).
Johannes P. A. M. van Loon   +6 more
wiley   +1 more source

Bimanual Manipulation of Steady Hand Eye Robots with Adaptive Sclera Force Control: Cooperative vs. Teleoperation Strategies [PDF]

open access: yesarXiv
Performing retinal vein cannulation (RVC) as a potential treatment for retinal vein occlusion (RVO) without the assistance of a surgical robotic system is very challenging to do safely. The main limitation is the physiological hand tremor of surgeons. Robot-assisted eye surgery technology may resolve the problems of hand tremors and fatigue and improve
arxiv  

Ginsenoside Rg1 inhibits angiogenesis in diabetic retinopathy through the miR‐100‐3p/FBXW7/c‐MYC molecular axis

open access: yesJournal of Diabetes Investigation, EarlyView.
Ginsenoside Rg1 attenuates diabetes‐induced retinal angiogenesis in vivo. ABSTRACT Aims/Introduction Ginsenoside Rg1 is an active ingredient found mainly in ginseng that has a variety of pharmacological effects, such as hypoglycemic, antioxidant, and anti‐inflammatory effects, and it inhibits vascular formation. In this study, we explored the effect of
Liping Xue   +8 more
wiley   +1 more source

Biomechanical properties of the sclera in patients with different types of refraction

open access: yesОфтальмохирургия, 2016
Purpose. To determine biomechanical age-specific features of the scleral tissue and the axial length of the eye.Material and methods. The study investigated 144 isolate d fragments of the sclera of 38 cadaver human eyes at the age from 40 to 75 years ...
E. V. Egorova   +5 more
doaj  

An anatomical investigation of alkaptonuria: Novel insights into ochronosis of cartilage and bone

open access: yesJournal of Anatomy, EarlyView.
Examination of an alkaptonuria body highlights the susceptibility of all cartilage types and associated perichondrium to ochronotic pigmentation and the heterogeneity of ochronotic pigment distribution both within and between tissues. In joints, calcified cartilage pigments before non‐calcified cartilage.
Juliette H. Hughes   +8 more
wiley   +1 more source

Histological analysis of retinal development and remodeling in the brown anole lizard (Anolis sagrei)

open access: yesJournal of Anatomy, EarlyView.
The fovea, a pit in the retina, is crucial for high‐acuity vision and is present in humans and a select group of vertebrates, including certain primates, birds, lizards, and fish. The development of the fovea has been a longstanding and hotly debated topic.
Ashley M. Rasys   +7 more
wiley   +1 more source

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