Results 131 to 140 of about 66,828 (272)

An unsupervised approach for eye sclera segmentation

open access: yes, 2018
We present an unsupervised sclera segmentation method for eye color images. The proposed approach operates on a visible spectrum RGB eye image and does not require any prior knowledge such as eyelid or iris center coordinate detection.
Riccio D   +3 more
core   +1 more source

Hyaluronan in Ocular Surface Health and Disease: From Biological Mechanisms to Therapeutic Applications

open access: yesProteoglycan Research, Volume 4, Issue 4, October 2026.
ABSTRACT Hyaluronan (HA) is an ubiquitous non‐sulfated glycosaminoglycan with unique physicochemical and biological properties that underpin its essential roles in tissue homeostasis, repair, and diseases. First identified in the vitreous humor of the eye, HA has a long‐standing history in ophthalmology as a key component of ophthalmic visco‐surgical ...
Sudhir Verma   +3 more
wiley   +1 more source

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

open access: yesVIEW, Volume 7, Issue 5, October 2026.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf   +5 more
wiley   +1 more source

Second-harmonic generation microscopy of murine scleral remodeling by collagenase and reparative collagen mimetic peptides

open access: yesFrontiers in Medicine
IntroductionMyopia, resulting from an excessive axial elongation of the eye, is increasing worldwide at alarming rates. This investigation is a pilot study to determine if a novel collagen mimetic peptide (CMP) has a reparative function for scleral ...
Daniel E. Savage   +14 more
doaj   +1 more source

Insights into the modulation of age‐related macular degeneration: Molecular and systems‐level perspectives

open access: yesActa Ophthalmologica, Volume 104, Issue S293, Page S4-S35, October 2026.
ENGLISH SUMMARY In developed countries, age‐related macular degeneration (AMD) is the leading cause of visual impairment in the aging population. Understanding of its pathogenesis is limited and the number of patients is predicted to continue rising. AMD is classified into two main forms: dry and neovascular AMD (dAMD and nAMD, respectively).
Hanna Heloterä
wiley   +1 more source

Differential effects of aging on transport properties of anterior and posterior human sclera.

open access: yes, 2016
The transport properties and composition of 44 pairs of human sclera, 37-91 years were compared. Solute transport, diffusion and partition coefficients of posterior sclera for solutes ranging in mass from 0.023-70kDa were higher than those of anterior ...

core   +1 more source

Extended Double Plasma Molecular Adsorption Sessions and Bilirubin Clearance: A Case Report

open access: yesHemodialysis International, Volume 30, Issue 4, Page 817-822, October 2026.
ABSTRACT Background The double plasma molecular adsorption system is an artificial‐liver treatment model combining the use of ion exchange resins and neutral microporous resins to remove toxins such as inflammatory cytokines without consuming large amounts of plasma and albumin. Given the relatively expensive consumables needed for Bilirubin adsorption,
Hui Ye   +7 more
wiley   +1 more source

Scleral collagen crosslinking as a promising direction of sclera-strengthening treatment of progressive myopia

open access: yesРоссийский офтальмологический журнал
The review presents recent research works on new technologies of scleral collagen crosslinking, a promising approach to sclerastrengthening treatment of progressive myopia.
E. N. Iomdina   +4 more
doaj   +1 more source

Spontaneous Hepatobiliary Disease in a Breeding Colony of Aotus spp.

open access: yesJournal of Medical Primatology, Volume 55, Issue 5, October 2026.
ABSTRACT Background Owl monkeys are nonhuman primate species in the genus Aotus. The Michale E. Keeling Center for Comparative Medicine and Research maintains an Owl Monkey Breeding and Research Resource composed of four species of owl monkeys: Aotus nancymai, A. vociferans, A. azarae, and A. griseimembra.
M. E. Hensel   +4 more
wiley   +1 more source

Biochemical changes in rabbit sclera following destruction of pigment epithelium

open access: yes, 1991
Øjensygdomme, sclera, pigmentepithelium, hydroxyproline, sodium iodate, glycosaminoqlycans, uronic ...
Trier, Klaus   +2 more
core   +1 more source

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