Results 71 to 80 of about 8,078 (179)

Humanin Mitigates Aβ‐Induced Retinal Pigment Epithelium Injury via AMPK‐Beclin1‐Dependent Mitophagy

Aging Cell, Volume 25, Issue 7, July 2026.
Humanin (HN) enhanced the clearance of Aβ‐accumulated mitochondria in the RPE while preserving retinal function and RPE barrier integrity. HN activated AMP‐activated protein kinase (AMPK), leading to phosphorylation of ULK1 and Beclin1, which promoted the interaction between Beclin1 and Parkin and their translocation to mitochondria.
Ha Young Jang, Suyeon Choi, Soo‐Jin Kim, Sooyun Kim, Dong Hyun Jo, Tae Geol Lee, Kyu‐Sang Park, Jeong Hun Kim   +7 more
wiley   +1 more source

MYCN Amplification in RB1‐Inactivated Retinoblastoma: Association With High‐Risk Features

Pediatric Blood &Cancer, Volume 73, Issue 6, June 2026.
ABSTRACT Background MYCN amplification occurs in a subset of retinoblastoma cases, both with and without RB1 inactivation. It has been suggested that retinoblastomas with MYCN amplification represent a distinct entity with more aggressive clinical behavior.
Kyriaki Papaioannou, Regina Kubica, Karen Fischhuber, Jasmin Beygo, Madlen Reschke, Petra Ritter‐Sovinz, Eva Biewald, Petra Ketteler, Dietmar Lohmann, Deniz Kanber   +9 more
wiley   +1 more source

Modified Four-Point Scleral Fixated Sutured Posterior Chamber Intraocular Lens Implantation Using 2 Eyelets Polymethyl Methacrylate Lens and 8-0 Polypropylene Suture

Clinical Ophthalmology, 2023
Natalia Christina Angsana,1 Firman Setya Wardhana,1 Supanji,1 Mohammad Eko Prayogo,2 Muhammad Bayu Sasongko1 1Department of Ophthalmology, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada – Sardjito Eye Center, Dr.
Angsana NC, Wardhana FS, Supanji, Prayogo ME, Sasongko MB   +4 more
doaj  

Safe Suture Burial in Trans-scleral Fixation of Posterior Chamber Intraocular Lens

Delhi Journal of Ophthalmology, 2011
The commonest complication of trans-scleral fixation of posterior chamber intraocular lens (PCIOL) is suture erosion. The sutures though crucial for lens stability, if exposed cause discomfort and are a potential source of endophthalmitis.
Ruchi Goel, KPS Malik
doaj   +1 more source

Retention of the Full Visual Opsin Repertoire in Some Australian Cryptozoic Lizards

Ecology and Evolution, Volume 16, Issue 6, June 2026.
This study investigates the link between visual evolution and fossorial habits in the endemic Australian skink genus Lerista. We provide evidence for positive site‐specific selection in all 4 cone opsins, as well as relaxed selection specific to LWS. We also provide evidence of selection linked to limb reduction, an indicator of fossorial adaptation ...
Matthew J. R. Ford, Alastair J. Ludington, Tessa Bradford, Kate L. Sanders, Mark N. Hutchinson, Bruno F. Simões   +5 more
wiley   +1 more source

Ciliary muscle thickness and intraocular pressure before and after latanoprost

Optometry and Vision Science, Volume 103, Issue 6, June 2026.
ABSTRACT Purpose To test the hypothesis that a larger, latanoprost‐induced intraocular pressure (IOP) reduction is associated with a thicker ciliary muscle. Methods Participants (N = 31) were healthy with the following details: mean ± SD age 24.8 ± 3.3 years.
Emily Slywka, Chiu‐Yen Kao, Melissa D. Bailey   +2 more
wiley   +1 more source

Modified Intraocular Lens Intrascleral Fixation Technique Using Two Vitrectomy Ports as Lens Haptic Fixation Sites

Clinical Ophthalmology, 2020
Yukihiko Suzuki, Toshio Tando, Kobu Adachi, Takashi Kudo, Mitsuru Nakazawa Department of Ophthalmology, Hirosaki University Graduate School of Medicine, Hirosaki 036-8562, JapanCorrespondence: Yukihiko Suzuki Tel +81-172-39-5095Fax +81-172-37-5735Email ...
Suzuki Y, Tando T, Adachi K, Kudo T, Nakazawa M   +4 more
doaj  

Axial length, myopia progression, and myopic maculopathy in Stickler syndrome

Acta Ophthalmologica, Volume 104, Issue 4, Page 423-430, June 2026.
Abstract Purpose We lack knowledge on the potentially progressive nature of and the prevalence of complications to myopia as a characteristic trait of Stickler syndrome. Methods This cross‐sectional study combines ophthalmic examination and medical record data on Danish patients with genetically confirmed Stickler syndrome type 1 (COL2A1) and type 2 ...
Kirstine B. Boysen, Mette Bertelsen, Nanna D. Rendtorff, Stense Farholt, Line Kessel   +4 more
wiley   +1 more source

In-and-out technique for intraocular lens scleral fixation

Clinical Ophthalmology, 2018
Jung Yeol Choi,1 Young Keun Han2,3 1Department of Ophthalmology, Jeju National University Hospital, Jeju, South Korea; 2Department of Ophthalmology, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, South Korea ...
Choi JY, Han YK
doaj  

Vitreoretinal complications and surgical outcomes in patients with X‐linked retinoschisis

Acta Ophthalmologica, Volume 104, Issue 4, Page 410-422, June 2026.
Abstract Purpose X‐linked retinoschisis (XLRS) is an inherited vitreoretinal disorder characterized by macular retinoschisis. In a subgroup of patients, peripheral retinoschisis can occur, potentially leading to complications such as vitreous haemorrhage (VH) and retinal detachment (RD).
Jonathan Hensman, Leo C. Hahn, Mary J. van Schooneveld, Roselie M. H. Diederen, Filip van den Broeck, Jacoline B. Ten Brink, Alberta A. Thiadens, Maria M. van Genderen, L. Ingeborgh van den Born, Bart P. Leroy, Carel B. Hoyng, Camiel J. F. Boon   +11 more
wiley   +1 more source