Results 111 to 120 of about 529,119 (224)

Mesenchymal Stem Cell‐Derived Extracellular Vesicles Ameliorate NaIO3‐Induced Dry AMD by Delivering miR‐486‐3p to Inhibit Lipocalin‐2‐Mediated Ferroptosis

MedComm, Volume 7, Issue 10, October 2026.
Our study reveals a novel mechanism by which MSC‐derived EVs alleviate NaIO3‐induced dry AMD‐like pathology. MSC‐EVs deliver miR‐486‐3p into retinal cells to directly inhibit the ferroptosis‐promoting target gene Lcn2. Concurrently, downregulated Lcn2 restores intracellular Gpx4 expression, thereby suppressing ferroptosis and rescuing retinal ...
Zheng Li, Tujing Zhao, Lin Ye, Runze Li, Huaping Tian, Ruilin Liao, Lulin Huang   +6 more
wiley   +1 more source

A Whole‐Head Finite Element Model for Electrical Neuromodulation via Visual Brain‐Machine Interfaces

Advanced Science, Volume 13, Issue 52, 18 September 2026.
A multimodal, personalized head model is presented that integrates the entire visual pathway with surrounding tissues to simulate electrical stimulation of the optic nerve. In vivo validation in humans and goats, plus systematic component‐elimination analysis, demonstrates the high accuracy of the comprehensive model.
Shengjian Lu, Tonghe Yang, Yuan Geng, Huan Wu, Yangrui Huang, Te Zheng, Haodi Chen, Shurui Huang, Yi Cao, Jian Yang, Wentao Yan, Yikui Zhang, Wencan Wu   +12 more
wiley   +1 more source

Bibliometric and visual analysis of scleral contact lenses: global characteristics and research trends from 1976 to 2023 [PDF]

International Journal of Ophthalmology
AIM: To gain insight into the future research directions in scleral contact lenses (SCLs) through a comprehensive bibliometrics study. METHODS: The publications related to SCLs were screened from the Web of Science Core Collection (WOSCC) database.
Jing Gao, Yao Xu
doaj   +1 more source

The Ultrastructure of the Spectacle, Cornea and Conjunctiva of the Short‐Nosed Sea Snake Aipysurus apraefrontalis (Elapidae, Squamata) With Particular Reference to the Sub‐Spectacular Space and Its Contents

Journal of Morphology, Volume 287, Issue 9, September 2026.
Using micro computed tomography, light microscopy and transmission electron microscopy, this study reveals that the conjunctival portions of the corneal epithelial and spectacular endothelial lining in the eye of the short‐nosed sea snake Aipysurus apraefrontalis possess high densities of microvilli to increase the surface area and two types of ...
H. Barry Collin, Boyin Liu, Sarah Wilson, Jenna M. Crowe‐Riddell, Shaun P. Collin   +4 more
wiley   +1 more source

Scleral Lens Case Report Series: Beyond the Corneal Borders [PDF]

, 2012
[From the introduction] Large diameter contact lenses that have their resting point beyond the corneal borders are believed to be among the best vision correction options for irregular corneas; they can postpone or even prevent surgical intervention as ...
van der Worp, Eef
core  

Whole‐Exome Sequencing Identifies Novel CPAMD8 Variants in Congenital Cataract and Candidate Variants in Pathologic Myopia

Molecular Genetics &Genomic Medicine, Volume 14, Issue 9, September 2026.
Whole‐exome sequencing identified compound heterozygous CPAMD8 variants supporting a congenital cataract phenotype in one family and candidate CPAMD8 variants in a second family with pathologic myopia, highlighting the need for segregation and functional validation.
Qiu‐ling Xie, Qiao Wang, Yanan Liu, Teng Huang, Jin Li   +4 more
wiley   +1 more source

Objective and subjective performance of scleral lenses and new advances in scleral lens technologies [PDF]

, 2015
Scleral lenses are widely recognized for their ability to markedly improve quality of life and giving back patients their ability to perform daily activities, mainly as a result of restoring visual function and/or reduction of ocular discomfort and pain ...
Visser, E.S.
core  

Ocular surface homeostasis after scleral lens usage

, 2023
: Objectives:The aim of this prospective study is to examine the effects of 5 hours of well-fitted, mini-scleral contact lens (mini-SL) wear on the tear film cytokine expression in healthy eyes.Methods:Twenty-three healthy participants were included in ...
Consejo, Alejandra, Ballet, Brice, Koppen, Carina, Reppe, Sjur, Behaegel, Jos\ue9phine, Utheim, Tor Paaske, N\ued Dhubhghaill, Sorcha, Aass, Hans Christian   +7 more
core  

Long-term follow-up after scleral lens fixation in patients with Marfan syndrome

BMC Ophthalmology, 2017
Background The dislocation of the crystalline lens is a common finding in patients with Marfan syndrome (MFS). Scleral intraocular lens (IOL) fixation is an accepted treatment method of this complication. To now, no long-term data on scleral IOL fixation
Jan Luebke, Thomas Reinhard, Hansjuergen Agostini, Daniel Boehringer, Philipp Eberwein   +4 more
doaj   +1 more source

Fiber Bragg Grating Force Sensors for Minimally Invasive Surgery: State of the Art, Challenges, and Opportunities

SmartBot, Volume 2, Issue 3, September 2026.
This article reviews the application of fiber Bragg grating (FBG) technology for precise force sensing in minimally invasive surgery. It outlines the fundamental working principles and algorithms used to interpret sensor data. The text surveys clinical applications across various medical fields, such as ophthalmology and vascular intervention (Table of
Shiyuan Dong, Tianqi Huang, Lingyu Chen, Shucong Yin, Qing Chang, Dingpei Han, Yangxi Li, Boyu Zhang, Hongen Liao, Fang Chen   +9 more
wiley   +1 more source