Results 201 to 210 of about 27,956 (253)

MicroRNA Expression Abnormalities in Limited Cutaneous Scleroderma and Diffuse Cutaneous Scleroderma

Journal of Clinical Immunology, 2012
Scleroderma (systemic sclerosis, SSc) is a complex autoimmune disease caused by progressive fibrotic replacement of normal tissue architecture, a progressive and ultimately fatal process that currently has no cure. Although dysregulation of microRNAs (miRNAs) is known to be involved in a variety of pathophysiologic processes, the role of miRNAs in SSc ...
Honglin, Zhu, Yisha, Li, Shunlin, Qu, Hui, Luo, Yaou, Zhou, Yanping, Wang, Hongjun, Zhao, Yunhui, You, Xianzhong, Xiao, Xiaoxia, Zuo   +9 more
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Antimitochondrial Antibodies and Their Significance in Diffuse and Limited Scleroderma

JCR: Journal of Clinical Rheumatology, 1999
The increased prevalence of primary biliary cirrhosis (PBC) in Sjogren's syndrome and scleroderma has been described. We determined the frequency of antimitochondrial antibodies (AMA) in limited scleroderma, compared with diffuse scleroderma, and have considered their clinical significance because they are known to be related to PBC.
J E, Pope, A, Thompson
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Caring for the Patient With Limited Systemic Scleroderma

Orthopaedic Nursing, 2016
Systemic scleroderma (systemic sclerosis) is a rare, autoimmune, collagen-vascular disease of unknown etiology that affects the connective tissues of the skin, internal organs, as well as the small blood vessels. There are 3 subclasses of systemic scleroderma: limited cutaneous, diffuse cutaneous, and sine scleroderma.
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Prevalence of Pulmonary Hypertension in Limited and Diffuse Scleroderma

Chest, 1996
To characterize the prevalence of undiagnosed pulmonary hypertension in patients with limited and diffuse scleroderma.Prospective cross-sectional study.University-based outpatient clinic.Thirty-four consecutive patients with limited (n = 29) or diffuse (n = 5) scleroderma but without the clinical diagnosis of pulmonary hypertension.All patients had 12 ...
R W, Battle, M A, Davitt, S M, Cooper, L M, Buckley, E S, Leib, P A, Beglin, M D, Tischler   +6 more
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Effects of olopatadine in limited scleroderma with peripheral eosinophils

Geriatrics & Gerontology International, 2008
Scleroderma and eosinophilia often occur together, though the pathogenesis is unclear. We investigated the effect of olopatadine hydrochloride in a series of cases of limited scleroderma (LS). Ten patients with LS and positive eosinophil counts (LSE) were enrolled (average age, 85 years; six men and four women).
Motoo, Kikuchi, Toshiaki, Inagaki, Hidekazu, Hanaki, Shinsuke, Harada, Ryuzo, Ueda   +4 more
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Diffuse and limited cutaneous systemic scleroderma

Current Opinion in Rheumatology, 2000
Juvenile systemic scleroderma (jSSc) is a rare disease. Based on the first large data collection on this patient group, the disease course was demonstrated to differ from that in adults. The concept of persistence of maternal cells in patients with SSc remains pathogenetically fascinating, as does the resemblance with graft-versus-host-disease. In view
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